Cheap 2025 Downtown Clayton Hotels
Photo by Najib Tecle
Choose from 1734 Downtown Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
0.02 km from Downtown Clayton
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
AC Hotel St. Louis Clayton
227 South Central Ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
0.33 km from Downtown Clayton
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
Le Méridien St. Louis Clayton
7730 Bonhomme Ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
0.2 km from Downtown Clayton
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
The Ritz-Carlton, St. Louis
100 Carondelet Plaza, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
0.5 km from Downtown Clayton
Stay at this 5-star luxury hotel in St. Louis. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the room ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
13.13 km from Downtown Clayton
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
13.19 km from Downtown Clayton
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
9.18 km from Downtown Clayton
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln, St. Ann, MO
Free Cancellation
Reserve now, pay when you stay
10.44 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive, Fenton, MO
16.4 km from Downtown Clayton
Stay at this 3-star business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Pear Tree Inn St. Louis Near Union Station
2211 Market Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
11.01 km from Downtown Clayton
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
12.76 km from Downtown Clayton
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
Sonesta ES Suites St. Louis - Chesterfield
15431 Conway Rd, Chesterfield, MO
Free Cancellation
Reserve now, pay when you stay
18.67 km from Downtown Clayton
Stay at this hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
21C Museum Hotel St Louis
1528 Locust street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
11.83 km from Downtown Clayton
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
17.02 km from Downtown Clayton
Stay at this 3.5-star business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
Forest Park Hotel by MDR
5915 Wilson Ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
5.58 km from Downtown Clayton
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
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