Business Hotels in South Carolina

Start date: Check-in selected.
To Date
End date: Check-out

Check availability on South Carolina Business Hotels

Tonight
Sep 20 - Sep 21
Tomorrow
Sep 21 - Sep 22
Next weekend
Sep 26 - Sep 28
In two weeks
Oct 3 - Oct 5

Pick from 824 South Carolina Business Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for South Carolina business-friendly hotels

Comfort Inn Greenville - Haywood Mall
Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas

Comfort Inn Greenville - Haywood Mall

2.5 star property
8.0 out of 10, Very Good, (1003)
"Great stay"
Comfort Inn Greenville - Haywood Mall
Hyatt Place Charleston Airport/Convention Center
Free daily buffet breakfast

Hyatt Place Charleston Airport/Convention Center

3.0 star property
9.4 out of 10, Exceptional, (1092)
"Amazing stay"
Hyatt Place Charleston Airport/Convention Center
Sheraton Columbia Downtown Hotel
Restaurant

Sheraton Columbia Downtown Hotel

3.5 star property
8.4 out of 10, Very Good, (1009)
"Wonderful stay"
Sheraton Columbia Downtown Hotel
Town & Country Inn and Suites
Front of property

Town & Country Inn and Suites

3.0 star property
9.2 out of 10, Wonderful, (1555)
"Great place to stay "
Town & Country Inn and Suites
Sleep Inn at Greenville Convention Cente
Lobby

Sleep Inn at Greenville Convention Cente

2.5 star property
7.8 out of 10, Good, (1003)
"Very nice and friendly staff. Also, great breakfast!"
Sleep Inn at Greenville Convention Cente
La Quinta Inn & Suites by Wyndham Greenville Haywood
Exterior

La Quinta Inn & Suites by Wyndham Greenville Haywood

3.0 star property
7.4 out of 10, Good, (1057)
"We had a good stay. Staff was accommodating and had a good breakfast "
La Quinta Inn & Suites by Wyndham Greenville Haywood
Home2 Suites by Hilton Greenville Downtown
Terrace/patio

Home2 Suites by Hilton Greenville Downtown

3.0 star property
9.2 out of 10, Wonderful, (974)
"Clean and close to everything Greenville has to offer."
Home2 Suites by Hilton Greenville Downtown
Hyatt Place Greenville/Haywood
Microwave

Hyatt Place Greenville/Haywood

3.0 star property
7.8 out of 10, Good, (1008)
"great hotel"
Hyatt Place Greenville/Haywood
Sonesta Resort Hilton Head Island
Premium bedding, in-room safe, desk, laptop workspace

Sonesta Resort Hilton Head Island

4.0 star property
8.6 out of 10, Excellent, (1063)
"We had an amazing stay! Clean rooms and so many dining options inside the property. "
Sonesta Resort Hilton Head Island
Baymont by Wyndham Columbia Northwest
Restaurant

Baymont by Wyndham Columbia Northwest

2.5 star property
5.4 out of 10, (1006)
"Place was good "
Baymont by Wyndham Columbia Northwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South Carolina Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia