Boutique Hotels in South Carolina

Check availability on South Carolina Boutique Hotels

Pick from 51 South Carolina Boutique Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Restoration
Egyptian cotton sheets, premium bedding, pillowtop beds, minibar

The Restoration

4.0 star property
9.6 out of 10, Exceptional, (1033)
"Great room, great location and the staff could not be any nicer or more helpful."
The Restoration
The Vendue
1 bedroom, Egyptian cotton sheets, premium bedding, pillowtop beds

The Vendue

4.0 star property
9.4 out of 10, Exceptional, (603)
"Excellent hotel in great location with extra touches like mimosas in the lobby Saturday and Sunday, nightly cookies. The artwork is stunning and really adds to the ambiance."
The Vendue
City Loft Hotel
View from property

City Loft Hotel

3.5 star property
9.6 out of 10, Exceptional, (719)
"Great little place to stay! "
City Loft Hotel
86 Cannon Charleston - Adults Only
Frette Italian sheets, premium bedding, pillowtop beds, in-room safe

86 Cannon Charleston - Adults Only

4.5 star property
10.0 out of 10, Exceptional, (69)
"Beautiful setting, excellent staff, and walkable to King Street and surrounding area."
86 Cannon Charleston - Adults Only
Beaufort Inn
1 bedroom, premium bedding, individually decorated

Beaufort Inn

3.5 star property
9.2 out of 10, Wonderful, (1000)
"Spectacular old mansion. Charming waterfront town. "
Beaufort Inn
Zero George Street
Anson Suite | Frette Italian sheets, premium bedding, Tempur-Pedic beds, free minibar

Zero George Street

5.0 star property
9.8 out of 10, Exceptional, (344)
"Lovely small hotel in pretty garden setting, with luxe, very comfortable rooms. Convenient location, easy parking, and very accommodating staff. "
Zero George Street
Planters Inn
Breakfast, dinner served; American cuisine, garden views

Planters Inn

4.5 star property
9.4 out of 10, Exceptional, (1007)
"Beautiful property and perfect location! "
Planters Inn
Market Pavilion Hotel
Rooftop terrace

Market Pavilion Hotel

4.5 star property
9.4 out of 10, Exceptional, (1009)
"Great location, perfect for couples, comfortable rooms"
Market Pavilion Hotel
Hotel Domestique
Bar (on property)

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (29)
"This place is a hidden gem. It is beautiful in every way. The staff is wonderful. The restaurant was incredible. Can’t wait to go back for a longer stay."
Hotel Domestique
Rhett House Inn
Exterior

Rhett House Inn

4.0 star property
9.2 out of 10, Wonderful, (608)
"Great breakfast. Friendly and helpful staff. Convenient location."
Rhett House Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free