Byron Vacations

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Top Hotel Deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
14.41 km from city center
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S, Rochester, MN
14.95 km from city center
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE, Rochester, MN
17.15 km from city center
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW, Rochester, MN
14.43 km from city center
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
Aspen Select

Aspen Select

3.5 out of 5
1215 2nd St SW, Rochester, MN
13.12 km from city center
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw, Rochester, MN
14.24 km from city center
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw, Rochester, MN
12.85 km from city center
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway, Rochester, MN
14.67 km from city center
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE, Rochester, MN
16.8 km from city center
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
13.35 km from city center
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw, Rochester, MN
13.11 km from city center
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

3 out of 5
1125 2nd St Sw, Rochester, MN
13.27 km from city center
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic

3 out of 5
77 Woodlake Drive SE, Rochester, MN
16.19 km from city center
Stay at this 3-star family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2 out of 5
4210 Highway 52 North, Rochester, MN
11.97 km from city center
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Country Inn & Suites by Radisson, Rochester, MN

Country Inn & Suites by Radisson, Rochester, MN

2.5 out of 5
4323 Highway 52 North, West Frontage Rd, Rochester, MN
12 km from city center
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Don't see what you're looking for?
See all available properties in Byron
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Sep 23 - Tue, Oct 21
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$328 Roundtrip, found 4 days ago
$328
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Sep 23 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Tue, Oct 21, priced at $328 found 4 days ago
Delta
Thu, Sep 25 - Tue, Oct 21
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$348 Roundtrip, found 4 days ago
$348
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Sep 25 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Tue, Oct 21, priced at $348 found 4 days ago
American Airlines
Thu, Sep 25 - Sat, Oct 18
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$348 Roundtrip, found 2 days ago
$348
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Sep 25 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Sat, Oct 18, priced at $348 found 2 days ago
American Airlines
Thu, Sep 25 - Sat, Oct 18
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$354 Roundtrip, found 2 days ago
$354
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Sep 25 from Hartsfield-Jackson Atlanta Intl. to Rochester Intl., returning Sat, Oct 18, priced at $354 found 2 days ago