Byron Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw Rochester MN
Book a stay at this family-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...
The Berkman
217 14th Ave SW Rochester MN
Book a stay at this golf aparthotel in Rochester. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the helpful ...
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Hampton Inn Rochester-South
1755 S Broadway Rochester MN
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Staybridge Suites Rochester - Mayo Clinic Area by IHG
101 11th Ave SW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
Brentwood Inn & Suites
123 Fourth Ave. NW Rochester MN
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the breakfast and the ...
Super 8 by Wyndham Rochester Mayo Clinic Area
106 SE 21st Street Rochester MN
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Sat, Sep 5 - Sun, Sep 6
DTW
Detroit Metropolitan Wayne County
RST
Rochester Intl.
$288
Roundtrip
found 16 hours ago
Fri, Aug 21 - Wed, Sep 2
DTW
Detroit Metropolitan Wayne County
RST
Rochester Intl.
$323
Roundtrip
found 1 day ago
Sat, Sep 5 - Tue, Sep 8
DTW
Detroit Metropolitan Wayne County
RST
Rochester Intl.
$337
Roundtrip
found 14 hours ago
Sat, Sep 5 - Sun, Sep 6
DTW
Detroit Metropolitan Wayne County
RST
Rochester Intl.
$368
Roundtrip
found 16 hours ago
Best points of interest in Byron
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