Vance Vacations

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Top Hotel Deals

Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
7.35 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
7.36 km from city center
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy Santee SC
6.85 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
6.89 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
7.54 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
Days Inn by Wyndham St George

Days Inn by Wyndham St George

2.5 out of 5
139 Motel Dr St. George SC
31.55 km from city center
Book a stay at this business-friendly hotel in St. George. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Peach Tree Inn

Peach Tree Inn

2.5 out of 5
111 Conners Dr St. George SC
22.49 km from city center
Book a stay at this business-friendly motel in St. George. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Jennie J McMahan Library and ...
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd Santee SC
7.51 km from city center
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
6.94 km from city center
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg

2.5 out of 5
663 Citadel Road Orangeburg SC
37.33 km from city center
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway Santee SC
7.66 km from city center
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Bells Marina & Resort

Bells Marina & Resort

2.5 out of 5
12907 Old Number Six Hwy Eutawville SC
11.69 km from city center
Book a stay at this golf aparthotel in Eutawville. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions ...
Budget Inn By Belvilla St George I-95

Budget Inn By Belvilla St George I-95

2.5 out of 5
104 Interstate Drive St. George SC
31.79 km from city center
Stay at this hotel in St. George. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Saint George Public Library and Jennie J McMahan ...
Red Roof Inn St George, SC

Red Roof Inn St George, SC

2.5 out of 5
115 Winningham Road St. George SC
31.52 km from city center
Book a stay at this business-friendly hotel in St. George. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy Santee SC
6.68 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Don't see what you're looking for?
See all available properties in Vance
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Tue, Feb 17 - Mon, Feb 23
EWR
Newark Liberty Intl. Airport
CHS
Charleston Intl.
$68 Roundtrip, found 3 days ago
$68
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, Feb 17 from Newark Liberty Intl. Airport to Charleston Intl., returning Mon, Feb 23, priced at $68 found 3 days ago
Delta
Wed, Feb 18 - Mon, Feb 23
JFK
John F. Kennedy Intl.
CHS
Charleston Intl.
$117 Roundtrip, found 1 day ago
$117
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Feb 18 from John F. Kennedy Intl. to Charleston Intl., returning Mon, Feb 23, priced at $117 found 1 day ago
JetBlue Airways
Sun, Feb 1 - Wed, Feb 18
JFK
John F. Kennedy Intl.
CHS
Charleston Intl.
$123 Roundtrip, found 1 day ago
$123
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Sun, Feb 1 from John F. Kennedy Intl. to Charleston Intl., returning Wed, Feb 18, priced at $123 found 1 day ago
United
Sun, Feb 15 - Wed, Feb 25
EWR
Newark Liberty Intl. Airport
CHS
Charleston Intl.
$123 Roundtrip, found 20 hours ago
$123
Roundtrip
found 20 hours ago
Select United flight, departing Sun, Feb 15 from Newark Liberty Intl. Airport to Charleston Intl., returning Wed, Feb 25, priced at $123 found 20 hours ago
American Airlines
Sat, Jan 17 - Tue, Jan 20
BOS
Logan Intl.
CHS
Charleston Intl.
$167 Roundtrip, found 23 hours ago
$167
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Logan Intl. to Charleston Intl., returning Tue, Jan 20, priced at $167 found 23 hours ago