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Comfort Inn & Suites Santee

2.5 star property
Guests relax by the lobby's cozy fireplace after exploring downtown attractions or recharge with modern amenities including WiFi and convenient laundry services

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Photo gallery for Comfort Inn & Suites Santee

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes - Comfort Inn & Suites Santee (Santee)
Free buffet breakfast - Comfort Inn & Suites Santee (Santee)
Lobby - Comfort Inn & Suites Santee (Santee)
Lobby - Comfort Inn & Suites Santee (Santee)
Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes - Comfort Inn & Suites Santee (Santee)
Located in the entertainment district, Comfort Inn & Suites Santee offers a free breakfast buffet and a cozy lobby fireplace. Enjoy the gym, business center, or seasonal outdoor pool. Helpful staff and on-site laundry ensure a hassle-free stay.

Reviews

8.0 out of 10
Very good

Popular amenities

  • Pool
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym

Room options

Available filters for rooms
Showing 10 of 10 rooms

View all photos for Standard Room, 1 King Bed

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Standard Room, 1 King Bed

9.2 out of 10
Wonderful
(24 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Standard Room, 2 Queen Beds

7.8 out of 10
Good
(33 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, Non Smoking

7.8 out of 10
Good
(26 reviews)
  • Sleeps 6
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Room, 1 King Bed, Accessible, Non Smoking

8.6 out of 10
Excellent
(8 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Room, 2 Queen Beds, Accessible, Non Smoking

9.0 out of 10
Wonderful
(9 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed, Accessible, Non Smoking

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, Multiple Beds, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, Multiple Beds, Accessible, Non Smoking

8.4 out of 10
Very good
(7 reviews)
  • Sleeps 6
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

  • Sleeps 4
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

About the neighborhood

Located in Santee, Comfort Inn & Suites Santee is in the entertainment district. Santee Cooper Country Club and Santee National Golf Club are worth checking out if an activity is on the agenda, while those wishing to experience the area's natural beauty can explore Santee State Park and Santee National Wildlife Refuge. Visit our Santee travel guide
Map
221 Britain St, Santee, SC, 29142

What's nearby

  • Santee Cooper Country Club
    13 min walk - 0.7 miles
  • Santee State Park
    16 min walk - 0.9 miles
  • Santee National Golf Club
    1 min drive - 1.3 miles
  • Santee Town Hall
    2 min drive - 1.3 miles
  • South Carolina State University
    27 min drive - 29.0 miles

Getting around

  • Charleston Intl. Airport (CHS)
    58 min drive

Restaurants

  • McDonald's
    4 min walk
  • Starbucks
    9 min walk
  • Armando’s Mexican Restaurant
    18 min walk
  • Elloree Truckstop & Diner
    11 min drive
  • Cracker Barrel
    5 min walk

About this property

Comfort Inn & Suites Santee

Hotel in the entertainment district, remodeled in 2023
You can look forward to a free breakfast buffet, laundry facilities, and a fireplace in the lobby at Comfort Inn & Suites Santee. Stay connected with free in-room WiFi, and guests can find other amenities such as a gym and a business center.
You'll also enjoy the following perks during your stay:
  • A seasonal outdoor pool
  • Free self parking
  • A TV in the lobby, a computer station, and free newspapers
  • A 24-hour front desk, multilingual staff, and an elevator
  • Guest reviews give top marks for the helpful staff
Room features
All 61 rooms boast comforts such as premium bedding and air conditioning, in addition to perks like free WiFi.
Other amenities include:
  • Frette Italian sheets, pillowtop mattresses, and free cribs/infant beds
  • Bathrooms with shower/tub combinations and hair dryers
  • Plasma TVs with satellite channels
  • Coffee/tea makers, heating, and daily housekeeping

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Limited onsite self parking
  • Wheelchair-accessible parking available

Food and drink

  • Free buffet breakfast
  • Coffee and tea in common areas

Things to do

  • Gym
  • Seasonal outdoor pool
  • TV in common areas

Family friendly

  • In-room crib
  • Laundry facilities
  • Seasonal outdoor pool

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Safe at front desk
  • Vending machine
  • Water dispenser

Guest services

  • Housekeeping (daily)
  • Multilingual staff

Business services

  • Business center
  • Computer station

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 4 accessible parking spaces
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Front entrance ramp
  • Lever door handles
  • Pool hoist on site
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom

More

  • 1 building
  • 3 floors
  • Designated smoking areas
  • Fireplace in lobby
  • Renovated entire property - December 2023

Room amenities

Bedroom

  • Blackout drapes
  • Free crib
  • Frette Italian sheets
  • Pillowtop mattress

Bathroom

  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • Plasma TV with satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Heating (climate-controlled)
  • Iron/ironing board
  • Phone

Policies

Check-in

Check-in time starts at 3:00 PM

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Children up to the age of 15 years can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Only bookings from non-local guests are accepted; guests whose residence is within 45 mi (72 km) of the property will not be allowed to check in
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property

We should mention

The seasonal pool will be open from March to October
Pool access available from 10 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation

Property is also known as

Comfort Inn Hotel Santee
Comfort Inn Santee
Comfort Inn Santee Hotel
Comfort Inn Suites Santee
Comfort & Suites Santee Santee
Comfort Inn & Suites Santee Hotel
Comfort Inn & Suites Santee Santee

Frequently asked questions

Does Comfort Inn & Suites Santee have a pool?

Yes, this property has a seasonal outdoor pool. Pool access is from 10 AM–10 PM.

Is Comfort Inn & Suites Santee pet-friendly?

No, only service animals are welcome at the property.

How much is parking?

Self parking is free at this property.

What time is check-in at Comfort Inn & Suites Santee?

Check-in begins at 3:00 PM.

What time is check-out at Comfort Inn & Suites Santee?

Check-out is at 11:00 AM.

Where is Comfort Inn & Suites Santee located?

Situated in the entertainment district, this hotel is within 1 mi (2 km) of Santee Cooper Country Club, Santee National Golf Club, and Santee Town Hall. Santee State Park and Lake Marion are also within 2 mi (3 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Comfort Inn & Suites Santee Reviews

8.0

Very Good

8.0

Cleanliness

8.2

Location

8.6

Staff & service

7.8

Property conditions & facilities
Rating 10 - Excellent. 426 out of 1004 reviews
Rating 8 - Good. 299 out of 1004 reviews
Rating 6 - Okay. 145 out of 1004 reviews
Rating 4 - Poor. 80 out of 1004 reviews
Rating 2 - Terrible. 54 out of 1004 reviews

Reviews

Verified

8/10 Good

Mary

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and basic, staff friendly, breakfast was a full buffet. Only downside was the noise from above and road noise from the nearby interstate.
Stayed 1 night in Apr 2026
Verified

8/10 Good

Dale

Liked: Cleanliness, amenities, property conditions & facilities
Clean rooms, nice staff, decent breakfast
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Kristi

Liked: Cleanliness, staff & service, amenities
Staff was very friendly and the room was large and very clean.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Tammi

Liked: Cleanliness, amenities, property conditions & facilities
The staff was excellent and the room was very clean. I would go there again.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Margarita

Liked: Cleanliness, staff & service, amenities
Overall nice room, friendly staff, and great breakfast. Very satisfied with my stay.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Shankar

Liked: Cleanliness, staff & service, property conditions & facilities
It was quite and comfortable stay
Stayed 1 night in Dec 2025
Verified

8/10 Good

Dorothy

Liked: Cleanliness, staff & service, amenities
Clean and comfortable. Staff very courteous!
Stayed 1 night in Jan 2026
Verified

8/10 Good

Shawn

Liked: Cleanliness, staff & service, amenities
Very kind staff and comfortable room
Stayed 1 night in Dec 2025
Verified

6/10 Okay

William

Liked: Staff & service, amenities
Hotel needs some renovation. Room was clean though. Front desk staff was nice.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Juan

Liked: Cleanliness, property conditions & facilities
Room and hotel was clean. Breakfast was great.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Fred

Clean. Great breakfast.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Judith

Liked: Cleanliness, amenities, property conditions & facilities
The room was very clean I really liked
Stayed 1 night in Dec 2025
Verified

6/10 Okay

Jennifer

Disliked: Cleanliness, amenities, property conditions & facilities
Staff was courteous. Hotel is outdated but was a fine place for an overnight stop.
Stayed 2 nights in Dec 2025
Verified

8/10 Good

Eugene

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and bathroom. The room was very large. Beds and pillows were comfortable. Breakfast was a standard fare.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Benjamin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Close to the highway with a safe location.
Stayed 1 night in Nov 2025
Verified

8/10 Good

Duc H

Liked: Cleanliness, property conditions & facilities
Clean room
Stayed 1 night in Feb 2026
Verified

8/10 Good

Kristina

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Breakfast had plenty of hot and cold options and was kept up. Room and lobby were clean and staff were friendly.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Judith

Liked: Cleanliness, amenities, property conditions & facilities
Nice and clean
Stayed 1 night in Jan 2026
Verified

6/10 Okay

Theresa

Liked: Cleanliness, staff & service
The hotel is a bit dated and not spanking clean looking. However, the beds and pillows are comfortable. Bed are firm.
Stayed 1 night in Jan 2026
Verified

6/10 Okay

Shannon

Disliked: Cleanliness, property conditions & facilities
Staff was nice and room was clean. It's just an older hotel. It is not a town or hotel I will be back to that's for sure. Just a place to lay your head.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Teresa S

Liked: Cleanliness, staff & service, amenities
Room was very clean
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities
Friendly staff room was clean
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Edith

Liked: Cleanliness, amenities, property conditions & facilities
The room was clean. Staff was very polite and friendly.
Stayed 3 nights in Oct 2025
Verified

8/10 Good

Elijah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was perfect and I also enjoyed the complementing breakfast in the morning
Stayed 2 nights in Jul 2025
Verified

8/10 Good

Priscilla

Liked: Cleanliness, amenities, property conditions & facilities
Front admin very kind upon arrival. Clean room and bed. When I called I hoped for more professional language and hospitable, but none the less we had a comfortable stay. First room we passed by the elevator smelled like weed. That was the only negative. Didn’t smell it anywhere else.
Stayed 1 night in Jan 2026