
South San Diego Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
South San Diego Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Little Italy Inn - Limited Service Apart Hotel
Downtown San Diego
Save 100% on your flight
per person
Sep 17 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this aparthotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Port of San Diego and USS Midway Museum are located nearby.

The Sofia Hotel
Downtown San Diego
Save 100% on your flight
per person
Sep 17 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 3.5-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.

Margaritaville Hotel San Diego Gaslamp Quarter
Downtown San Diego
Save 100% on your flight
per person
Sep 17 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4-star business-friendly hotel in San Diego. Enjoy a rooftop terrace, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.

The Beau Downtown San Diego Gaslamp Quar
Downtown San Diego
Save 100% on your flight
per person
Sep 17 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 3-star hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Petco Park and Port of San Diego are located nearby.

Alma San Diego Downtown, a Tribute Portfolio Hotel
Downtown San Diego
Save 100% on your flight
per person
Sep 17 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4-star boutique hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.

Westin Carlsbad Resort & Spa
Save 100% on your flight
per person
Sep 17 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4-star golf hotel in Carlsbad. Enjoy free WiFi, 4 restaurants, and room service. Popular attractions LEGOLAND® California and Carlsbad State Beach are located nearby.
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Gaylord Pacific Resort & Convention Center
1000 H Street, Chula Vista, CA
8.64 km from city center
Stay at this 4-star spa hotel in Chula Vista. Enjoy 3 outdoor pools, a full-service spa, and 8 restaurants. Popular attractions San Diego Bay and Hotel del Coronado ...

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct, San Diego, CA
8.44 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Handlery Hotel
950 Hotel Cir N, San Diego, CA
23.39 km from city center
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
19.96 km from city center
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
19.02 km from city center
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
27.99 km from city center
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...

Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
18.74 km from city center
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...

The Dextro Hotel, BW Premier Collection
1617 1st Avenue, San Diego, CA
19.63 km from city center
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
17.95 km from city center
Stay at this 4-star spa hotel in San Diego. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff ...

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place, San Diego, CA
24.4 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...

Lafayette Hotel & Club
2223 El Cajon Blvd, San Diego, CA
21.16 km from city center
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...

Hampton Inn San Diego/Mission Valley
2151 Hotel Circle South, San Diego, CA
23.84 km from city center
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...

The Little Italy Hotel Downtown San Diego
1646 Front St, San Diego, CA
19.76 km from city center
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in our reviews. ...
Don't see what you're looking for?
See all available properties in South San Diego
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Aug 10 - Thu, Aug 14
SFO
San Francisco Intl.
SAN
San Diego Intl.
$57 Roundtrip, found 5 days ago
$57
Roundtrip
found 5 days ago

Tue, Nov 11 - Wed, Nov 12
ORD
O'Hare Intl.
SAN
San Diego Intl.
$139 Roundtrip, found 2 days ago
$139
Roundtrip
found 2 days ago

Sat, Sep 6 - Sun, Sep 14
PDX
Portland Intl.
CLD
McClellan-Palomar
$187 Roundtrip, found 6 days ago
$187
Roundtrip
found 6 days ago

Wed, Aug 20 - Sat, Aug 30
DAL
Love Field
SAN
San Diego Intl.
$237 Roundtrip, found 3 days ago
$237
Roundtrip
found 3 days ago

Tue, Sep 2 - Sat, Sep 6
JFK
John F. Kennedy Intl.
SAN
San Diego Intl.
$237 Roundtrip, found 5 days ago
$237
Roundtrip
found 5 days ago
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