
Santo Spirito Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Santo Spirito Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Villa Tolomei Hotel & Resort
Oltrarno
Price was $1,492, price is now $1,096 per person
$1,096
per person
Apr 25 - Apr 30
found 9 hours ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
Book a stay at this luxury hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pitti Palace and Ponte Vecchio are located nearby.

Aurum Uffizi
Historic Centre of Florence
Price was $1,581, price is now $1,197 per person
$1,197
per person
Apr 19 - Apr 22
found 1 day ago
Roundtrip flight included
Columbus (CMH) to Florence (FLR)
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Uffizi Gallery and Palazzo Vecchio are located nearby.

Aurum Firenze
Historic Centre of Florence
Price was $1,485, price is now $1,159 per person
$1,159
per person
Apr 19 - Apr 22
found 1 day ago
Roundtrip flight included
Columbus (CMH) to Florence (FLR)
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Uffizi Gallery and Cathedral of Santa Maria del Fiore are located nearby.

Art Hotel Villa Agape
Oltrarno
Price was $1,467, price is now $1,156 per person
$1,156
per person
Apr 25 - Apr 30
found 9 hours ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Piazzale Michelangelo and Pitti Palace are located nearby.

Glance Hotel In Florence
Historic Centre of Florence
Price was $1,939, price is now $1,533 per person
$1,533
per person
Apr 25 - Apr 30
found 9 hours ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Uffizi Gallery and Cathedral of Santa Maria del Fiore are located nearby.

Hotel De La Ville
Historic Centre of Florence
Price was $1,815, price is now $1,461 per person
$1,461
per person
Apr 25 - Apr 30
found 9 hours ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
Book a stay at this family-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Cathedral of Santa Maria del Fiore and Piazza della Signoria are located nearby.
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Hotel Horto Convento
Viale Ariosto, 13 Florence FI
0.42 km from Santo Spirito
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Palazzo Mannaioni Suites
Via Maffia 9 - 17r Florence FI
0.93 km from Santo Spirito
Stay at this residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. Popular ...

UNA Hotels Vittoria Firenze
Via Pisana 59 Florence FI
0.49 km from Santo Spirito
Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...

La Torre Del Cestello
Via Borgo San Frediano, 8 Florence FI
0.86 km from Santo Spirito
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Pitti Palace and Ponte Vecchio are ...

Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49 Florence FI
0.78 km from Santo Spirito
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...

Casa Santo Nome di Gesù
Piazza del Carmine, 21 Florence FI
0.68 km from Santo Spirito
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...

Oltrarno Splendid
Via dei Serragli 7 Florence FI
0.89 km from Santo Spirito
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...

Palazzo Oliveto
Via Monte Oliveto Florence FI
0.3 km from Santo Spirito
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and a garden. Popular attractions Pitti Palace and Ponte Vecchio are located nearby.

B&B Mia Palace
Via della Fonderia 8 Florence FI
0.66 km from Santo Spirito
Stay at this affittacamere in Florence. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Popular attractions Pitti Palace and Ponte Vecchio are ...

1900 Artevita
Viale Raffaello Sanzio 2 Florence FI
0.49 km from Santo Spirito
Stay at this B&B in Florence. Enjoy free WiFi, breakfast (surcharge), and housekeeping. Popular attractions Pitti Palace and Ponte Vecchio are located ...

Ottantotto Firenze
Via dei Serragli 88 Florence FI
0.75 km from Santo Spirito
Stay at this guesthouse in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...

Residenza D'Epoca Al Numero 8
Via Borgo San Frediano n. 8 Florence FI
0.9 km from Santo Spirito
Stay at this B&B in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...

AdAstra Suites
Via Del Campuccio, 53 Florence FI
0.77 km from Santo Spirito
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Thu, Feb 19 - Mon, Feb 23
ORY
Orly
FLR
Peretola
$239 Roundtrip, found 3 days ago
$239
Roundtrip
found 3 days ago

Thu, Feb 19 - Mon, Feb 23
CDG
Roissy-Charles de Gaulle
FLR
Peretola
$245 Roundtrip, found 3 days ago
$245
Roundtrip
found 3 days ago

Thu, Feb 19 - Mon, Feb 23
CDG
Roissy-Charles de Gaulle
FLR
Peretola
$289 Roundtrip, found 3 days ago
$289
Roundtrip
found 3 days ago

Thu, Feb 19 - Mon, Feb 23
CDG
Roissy-Charles de Gaulle
FLR
Peretola
$341 Roundtrip, found 3 days ago
$341
Roundtrip
found 3 days ago

Thu, Feb 19 - Mon, Feb 23
CDG
Roissy-Charles de Gaulle
FLR
Peretola
$354 Roundtrip, found 3 days ago
$354
Roundtrip
found 3 days ago

