
Santo Spirito Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals

Hotel Horto Convento
Viale Ariosto, 13, Florence, FI
0.42 km from Santo Spirito
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...

UNA Hotels Vittoria Firenze
Via Pisana 59, Florence, FI
0.49 km from Santo Spirito
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...

Palazzo Mannaioni Suites
Via Maffia 9 - 17r, Florence, FI
0.93 km from Santo Spirito
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...

Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence, FI
0.78 km from Santo Spirito
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...

La Torre Del Cestello
Via Borgo San Frediano, 8, Florence, FI
0.86 km from Santo Spirito
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...

Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
0.68 km from Santo Spirito
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...

Hotel Firenze 2000
Viale Raffaello Sanzio, 16, Florence, FI
0.43 km from Santo Spirito
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Popular attractions Ponte Vecchio and Uffizi Gallery are located ...

Ostello Tasso
VIA VILLANI 15 , PIAZZA TASSO, Florence, FI
0.33 km from Santo Spirito
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and rainfall showerheads. Popular attractions Ponte Vecchio and Uffizi Gallery are located ...

L'Antica Porta Boutique B&B
Viale Francesco Petrarca, 122, Florence, FI
0.83 km from Santo Spirito
Stay at this B&B in Florence. Enjoy free WiFi, parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery are located ...

B&B Mia Palace
Via della Fonderia 8, Florence, FI
0.66 km from Santo Spirito
Stay at this affittacamere in Florence. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Popular attractions Ponte Vecchio and Cathedral of Santa ...

Oltrarno Splendid
Via dei Serragli 7, Florence, FI
0.89 km from Santo Spirito
Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...

Residenza D'Epoca Al Numero 8
Via Borgo San Frediano n. 8, Florence, FI
0.86 km from Santo Spirito
Stay at this B&B in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...

1900 Artevita
Viale Raffaello Sanzio 2, Florence, FI
0.49 km from Santo Spirito
Stay at this B&B in Florence. Enjoy free WiFi, breakfast (surcharge), and housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery are located ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Mar 10 - Fri, Mar 20
JFK
John F. Kennedy Intl.
FLR
Peretola
$383 Roundtrip, found 19 hours ago
$383
Roundtrip
found 19 hours ago

Tue, Mar 10 - Fri, Mar 20
JFK
John F. Kennedy Intl.
FLR
Peretola
$401 Roundtrip, found 19 hours ago
$401
Roundtrip
found 19 hours ago

Tue, Mar 10 - Fri, Mar 20
JFK
John F. Kennedy Intl.
FLR
Peretola
$405 Roundtrip, found 19 hours ago
$405
Roundtrip
found 19 hours ago

Tue, Mar 10 - Fri, Mar 20
JFK
John F. Kennedy Intl.
FLR
Peretola
$409 Roundtrip, found 19 hours ago
$409
Roundtrip
found 19 hours ago

Tue, Mar 10 - Fri, Mar 20
JFK
John F. Kennedy Intl.
FLR
Peretola
$416 Roundtrip, found 19 hours ago
$416
Roundtrip
found 19 hours ago
Best points of interest in Florence
- Piazza Santo Spirito Vacations
- Porta Romana Vacations
- Santo Spirito Basilica Vacations
- Santa Maria della Carmine Vacations
- Piazza del Carmine Vacations
- Brancacci Chapel Vacations
- Torrigiani Garden Vacations
- Church of St Felix Vacations
- Il Nabucco di Matteo Gabellini Vacations
- Uffizi Gallery Vacations
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More Types of Hotels
- Hotels with Air Conditioning in Santo Spirito
- Smoke Free Hotels in Santo Spirito
- Family Hotels in Santo Spirito
- Hotels with WiFi in Santo Spirito
- Hotel with wifi in Santo Spirito
- Hotels with Balconies in Santo Spirito
- Pet-friendly Hotels in Santo Spirito
- Hotels with Bars in Santo Spirito
- Hotels with Complimentary Breakfast in Santo Spirito
- Hotel with a Concierge in Santo Spirito
- Luxury Hotels in Santo Spirito
- Cheap Hotels in Santo Spirito
- Hotels with Fireplaces in Santo Spirito
- Hotels with a Pool in Santo Spirito
- Adults Only Resorts & Hotels in Santo Spirito
- Resorts & Hotels with Spas in Santo Spirito
- Hotels with smoking rooms in Santo Spirito
- Hotels with Hot Tubs in Santo Spirito