San Francisco Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Photo by Hideki Yamagata
Top Hotel Deals
JW Marriott Panama
Calle Punta Colon, Punta Pacifica, Panama City, Panama
1.9 km from San Francisco
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
2.31 km from San Francisco
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Megapolis Hotel Panamá
Avenida Balboa, Panama City
2.07 km from San Francisco
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Ramada Plaza By Wyndham Panama Punta Pacífica
Via Israel y Calle 71, San Francisco, Panama City, Panama
0.58 km from San Francisco
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Las Americas Golden Tower Panama
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
1.92 km from San Francisco
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
0.75 km from San Francisco
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro, Panama City, Panama
2.01 km from San Francisco
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Aloft Panama
Via Israel & Calle 76, Panama City, Panama
0.64 km from San Francisco
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall, Panama City, Panama
1.05 km from San Francisco
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Residence Inn by Marriott Panama City
CALLE RAMON H JURADO EDIFICO P, Panama City
1.71 km from San Francisco
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
San Francisco by Wynwood House
C. 73 Este, Panama City, Provincia de Panamá
0.06 km from San Francisco
Stay at this 4-star aparthotel in Panama City. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
1.99 km from San Francisco
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
15.65 km from San Francisco
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Thu, Aug 7 - Mon, Aug 11
MIA
Miami Intl.
PTY
Tocumen Intl.
$266 Roundtrip, found 2 days ago
$266
Roundtrip
found 2 days ago
Fri, Jul 11 - Thu, Jul 17
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$283 Roundtrip, found 3 days ago
$283
Roundtrip
found 3 days ago
Mon, Nov 24 - Thu, Dec 4
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$534 Roundtrip, found 4 days ago
$534
Roundtrip
found 4 days ago
Mon, Nov 24 - Mon, Dec 1
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$534 Roundtrip, found 4 days ago
$534
Roundtrip
found 4 days ago
Best points of interest in Panama City
- Multiplaza Pacific Mall Vacations
- Avenida Balboa Vacations
- ATLAPA Conventions Center Vacations
- Multicentro Panama Vacations
- Hospital Punta Pacífica Vacations
- Panama Canal Murals Vacations
- Pacific Center Vacations
- Omar Torrijos Recreational Park Vacations
- Colonial Religious Art Museum Vacations
- Albrook Shopping Mall Vacations
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