Panama Canal Zone Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Panama Canal Zone Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel

3.5 out of 5
Amador
per person
Aug 19 - Aug 23
found 1 day ago
Roundtrip non-stop flight included
Evansville (EVV) to Panama City (PTY)
Stay at this 3.5-star hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
per person
Aug 19 - Aug 23
found 1 day ago
Roundtrip non-stop flight included
Evansville (EVV) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

The Sands by Wynwood House

The Sands by Wynwood House

2 out of 5
Calidonia
Save 100% on your flight
per person
Aug 19 - Aug 23
found 1 day ago
Roundtrip non-stop flight included
Evansville (EVV) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi and an outdoor pool. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Casco View Apartments

Casco View Apartments

3 out of 5
Santa Ana
per person
Aug 19 - Aug 23
found 1 day ago
Roundtrip non-stop flight included
Evansville (EVV) to Panama City (PTY)
Stay at this 3-star condo in Panama City. Enjoy free WiFi, premium bedding, and in-room washers/dryers. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Arcadia Condo Suites

Arcadia Condo Suites

2.5 out of 5
Costa del Este
per person
Aug 19 - Aug 23
found 1 day ago
Roundtrip non-stop flight included
Evansville (EVV) to Panama City (PTY)
Stay at this aparthotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Multiplaza Pacific Mall and Avenida Balboa are located nearby.

The Westin Panama

The Westin Panama

4 out of 5
Costa del Este
per person
Aug 19 - Aug 23
found 1 day ago
Roundtrip non-stop flight included
Evansville (EVV) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy a full-service spa, breakfast (surcharge), and 24-hour room service. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall are located nearby.

Don't see what you're looking for?
See all available trips from Columbus to Panama Canal Zone
View all trips

Top Hotel Deals

Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
32.08 km from city center
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 out of 5
Amador Avenue & Van Hook Street, Panama City, Panama
34.18 km from city center
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff and the property condition ...
Summit Rainforest & Golf Resort

Summit Rainforest & Golf Resort

4 out of 5
Omar Torrijos Ave, Paraiso, Panama Canal, Panama City, Panama
19.6 km from city center
Stay at this 4-star golf hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
34.05 km from city center
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
35.98 km from city center
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
35.42 km from city center
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
43.32 km from city center
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
33.17 km from city center
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
36.26 km from city center
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
33.48 km from city center
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
35.7 km from city center
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
34.95 km from city center
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
34.64 km from city center
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
33.39 km from city center
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons, El Cangre, Bella Vista, Panama City, Panama
33.2 km from city center
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Don't see what you're looking for?
See all available properties in Panama Canal Zone
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.