Southern Illinois Hotel Rooms at the Best Western

Featured Southern Illinois Best Western Hotels

Best Western Delta Inn

Best Western Delta Inn

2.5 out of 5
1509 Hampton Dr Effingham IL
Free Cancellation
Reserve now, pay when you stay
Best Western Marion Hotel

Best Western Marion Hotel

2.5 out of 5
400 Comfort Dr Marion IL
Free Cancellation
Reserve now, pay when you stay
Best Western Saluki Inn

Best Western Saluki Inn

2.5 out of 5
801 N Giant City Rd Carbondale IL
Free Cancellation
Reserve now, pay when you stay
Best Western Troy Hotel

Best Western Troy Hotel

2.5 out of 5
2020 Formosa Drive Troy IL
Free Cancellation
Reserve now, pay when you stay
Best Western Heartland Inn

Best Western Heartland Inn

2.5 out of 5
1416 Broadway Avenue East Mattoon IL
Free Cancellation
Reserve now, pay when you stay
Best Western Flora Inn

Best Western Flora Inn

2.5 out of 5
201 Hagen Dr Flora IL
Free Cancellation
Reserve now, pay when you stay
Best Western U. S. Inn

Best Western U. S. Inn

2.5 out of 5
11640 State Route 127 Nashville IL
Free Cancellation
Reserve now, pay when you stay
Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights

2.5 out of 5
150 Ludwig Dr Fairview Heights IL
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.