Eastern Panama Vacation Packages for 2026

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Eastern Panama Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá

Hotel Casa Panamá

4 out of 5
Casco Viejo
Price was $797, price is now $646 per person
$646
per person
Jan 22 - Jan 26
found 5 hours ago
Roundtrip flight included
San Juan (SJU) to Panama City (PTY)
Stay at this hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,298, price is now $932 per person
$932
per person
Jan 22 - Jan 26
found 5 hours ago
Roundtrip flight included
San Juan (SJU) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $927, price is now $673 per person
$673
per person
Jan 22 - Jan 26
found 5 hours ago
Roundtrip flight included
San Juan (SJU) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Save 100% on your flight
Price was $1,841, price is now $1,346 per person
$1,346
per person
Jan 22 - Jan 26
found 5 hours ago
Roundtrip flight included
San Juan (SJU) to Panama City (PTY)
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

La Concordia Boutique Hotel

La Concordia Boutique Hotel

4 out of 5
Casco Viejo
Price was $1,384, price is now $1,126 per person
$1,126
per person
Jan 22 - Jan 26
found 5 hours ago
Roundtrip flight included
San Juan (SJU) to Panama City (PTY)
Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and onsite spa services. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Renaissance Panama City Hotel

Renaissance Panama City Hotel

5 out of 5
Bella Vista
Price was $835, price is now $692 per person
$692
per person
Jan 22 - Jan 26
found 5 hours ago
Roundtrip flight included
San Juan (SJU) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a casino. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

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Top Hotel Deals

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande Isla Grande Colon
160.42 km from city center
Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park ...
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
160.59 km from city center
Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National ...
Ranchos de Chalia

Ranchos de Chalia

3 out of 5
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
161.23 km from city center
Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ...
Konsenda San Blas

Konsenda San Blas

2 out of 5
Llano Cartí Km 11 El Llano Panamá Province
86.7 km from city center
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira Isla Grande Provincia de Colón
160.23 km from city center
Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ...
Ciel y Miel

Ciel y Miel

3 out of 5
Caillle Principale Cacique Provincia de Colón
164.99 km from city center
Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS

3 out of 5
El Porvenir Narganá Guna Yala
98.19 km from city center
Stay at this property in San Blas Islands. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Porvenir Museum and Isla Chichime are ...
San Blas Paradise Private Cabins on Shipwreck Island - meals included

San Blas Paradise Private Cabins on Shipwreck Island - meals included

2 out of 5
Perro Island Narganá Guna Yala
92.17 km from city center
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo ...
Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

2 out of 5
Diablo Island Narganá Guna Yala
92.59 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ...
Private Bedroom on Paradise San Blas Island

Private Bedroom on Paradise San Blas Island

2.5 out of 5
Isla Yansailadup Narganá Guna Yala
91.86 km from city center
Stay at this guesthouse in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Museum of the ...
Private Over the Water Cabin on San Blas Island

Private Over the Water Cabin on San Blas Island

2 out of 5
9.542876, -78.899058 Narganá San Blas
93 km from city center
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime ...
San Blas Private Beach Cabin

San Blas Private Beach Cabin

2.5 out of 5
Nusatupo Narganá Guna Yala
82.6 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
Private Over-Water Cabins on San Blas Island

Private Over-Water Cabins on San Blas Island

2.5 out of 5
C5W9 4M Nusatupo Narganá
88.56 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
Discovery Gunayar

Discovery Gunayar

2 out of 5
Archipiélago de San Blas Narganá Guna Yala
86.38 km from city center
Book a stay at this beach lodge in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime and Isla ...
Cabins in Asserya Island - San Blas paradise - meals included

Cabins in Asserya Island - San Blas paradise - meals included

2 out of 5
Aroma Island (Isla Anzuelo) Narganá Guna Yala
91.98 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a marina, and an airport shuttle (surcharge). Popular attractions Museum and Isla Chichime are ...
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See all available properties in Eastern Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sun, Dec 28 - Thu, Jan 1
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$230 Roundtrip, found 1 day ago
$230
Roundtrip
found 1 day ago
Select Copa flight, departing Sun, Dec 28 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jan 1, priced at $230 found 1 day ago
avianca
Sat, Dec 27 - Mon, Dec 29
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Dec 27 from Juan Santamaría Intl. to Tocumen Intl., returning Mon, Dec 29, priced at $263 found 1 day ago
United
Mon, Mar 16 - Tue, Mar 24
MIA
Miami Intl.
PTY
Tocumen Intl.
$364 Roundtrip, found 4 days ago
$364
Roundtrip
found 4 days ago
Select United flight, departing Mon, Mar 16 from Miami Intl. to Tocumen Intl., returning Tue, Mar 24, priced at $364 found 4 days ago
American Airlines
Sat, Mar 21 - Sun, Apr 19
MIA
Miami Intl.
PTY
Tocumen Intl.
$384 Roundtrip, found 4 days ago
$384
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Mar 21 from Miami Intl. to Tocumen Intl., returning Sun, Apr 19, priced at $384 found 4 days ago
Delta
Tue, Jan 13 - Tue, Jan 20
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$717 Roundtrip, found 1 hour ago
$717
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Jan 13 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Tue, Jan 20, priced at $717 found 1 hour ago