Eastern Panama Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Eastern Panama Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Arcadia Condo Suites
Costa del Este
Price was $806, price is now $662 per person
$662
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Stay at this aparthotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Multiplaza Pacific Mall and Avenida Balboa are located nearby.
Bristol Panama, a Registry Collection Hotel
Bella Vista
Price was $1,255, price is now $987 per person
$987
per person
Nov 26 - Nov 30
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
La Concordia Boutique Hotel
Casco Viejo
Price was $1,299, price is now $1,067 per person
$1,067
per person
Nov 26 - Nov 30
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and onsite spa services. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Las Americas Golden Tower Panama
San Francisco
Price was $1,053, price is now $874 per person
$874
per person
Nov 26 - Nov 30
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Hotel Casa Panamá
Casco Viejo
Price was $882, price is now $745 per person
$745
per person
Nov 26 - Nov 30
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 4-star hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the bar and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Victoria Hotel and Suites Panama
Bella Vista
Price was $842, price is now $725 per person
$725
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Don't see what you're looking for?
See all available trips from Columbus to Eastern Panama
View all tripsTop Hotel Deals
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3, Puerto Lindo, Colón
161.23 km from city center
Stay at this 3-star hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are ...
Ordovician Beach Resort
Isla Grande, Isla Grande, Colon
160.42 km from city center
Stay at this 4.5-star luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National ...
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Perro Island, Narganá, Guna Yala
92.17 km from city center
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo ...
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island, Narganá, Guna Yala
92.59 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ...
Hotel Cocotal
La Guaira, Isla Grande, Provincia de Colón
160.23 km from city center
Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ...
Ciel y Miel
Caillle Principale, Cacique, Provincia de Colón
164.99 km from city center
Stay at this 3-star beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
Konsenda San Blas
Llano Cartí Km 11, El Llano, Panamá Province
86.7 km from city center
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
Private Over the Water Cabin on San Blas Island
9.542876, -78.899058, Narganá, San Blas
93 km from city center
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime ...
Cabins in Asserya Island - San Blas paradise - meals included
Aroma Island (Isla Anzuelo), Narganá, Guna Yala
91.98 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a marina, and an airport shuttle (surcharge). Popular attractions Museum and Isla Chichime are ...
Discovery Gunayar
Archipiélago de San Blas, Narganá, Guna Yala
86.38 km from city center
Book a stay at this beach lodge in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime and Isla ...
Private bedroom on paradise San Blas Island - Meals Included
Isla Yansailadup, Narganá, Guna Yala
91.86 km from city center
Stay at this guesthouse in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Museum of the ...
Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir, Narganá, Guna Yala
98.19 km from city center
Stay at this 3-star property in San Blas Islands. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Porvenir Museum and Isla Chichime ...
Paradise Over the Water Cabins in San Blas
G4V2 48, Narganá, Guna Yala
98.35 km from city center
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Porvenir Museum ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Fri, Dec 5 - Sat, Dec 13
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$555 Roundtrip, found 1 day ago
$555
Roundtrip
found 1 day ago
Thu, Dec 4 - Tue, Dec 9
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$570 Roundtrip, found 1 day ago
$570
Roundtrip
found 1 day ago
Sun, Jun 14 - Tue, Jun 23
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$719 Roundtrip, found 3 days ago
$719
Roundtrip
found 3 days ago
Sun, Jun 14 - Tue, Jun 23
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$907 Roundtrip, found 3 days ago
$907
Roundtrip
found 3 days ago
Sun, Jun 14 - Tue, Jun 23
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$1,053 Roundtrip, found 3 days ago
$1,053
Roundtrip
found 3 days ago