Eastern Panama Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Eastern Panama Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Mahogany Suites
Price was $1,318, price is now $536 per person
$536
per person
Apr 8 - Apr 14
found 18 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $1,840, price is now $1,037 per person
$1,037
per person
Apr 8 - Apr 14
found 18 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hotel Riu Plaza Panama
Bella Vista
Save 100% on your flight
Price was $1,152, price is now $739 per person
$739
per person
Apr 8 - Apr 14
found 18 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Dreams Playa Bonita Panama - All Inclusive
Save 100% on your flight
Price was $1,968, price is now $1,420 per person
$1,420
per person
Apr 8 - Apr 14
found 18 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
La Concordia Boutique Hotel
Casco Viejo
Save 100% on your flight
Price was $1,678, price is now $1,227 per person
$1,227
per person
Apr 8 - Apr 14
found 18 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and onsite spa services. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
JW Marriott Panama
San Francisco
Price was $1,364, price is now $1,006 per person
$1,006
per person
Apr 8 - Apr 14
found 18 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
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See all available trips from Columbus to Eastern Panama
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HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
160.33 km from city center
Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National ...
Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
160.23 km from city center
Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ...
Konsenda San Blas
Llano Cartí Km 11 El Llano Panamá Province
86.7 km from city center
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
Private Over the Water Cabin on San Blas Island
9.542876, -78.899058 Narganá San Blas
93 km from city center
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime ...
Ordovician Beach Resort
Isla Grande Isla Grande Colon
160.42 km from city center
Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park ...
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
161.23 km from city center
Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ...
Ciel y Miel
Caillle Principale Cacique Provincia de Colón
164.99 km from city center
Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
98.19 km from city center
Stay at this property in San Blas Islands. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Porvenir Museum and Isla Chichime are ...
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Perro Island Narganá Guna Yala
92.17 km from city center
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo ...
San Blas Private Beach Cabin
Nusatupo Narganá Guna Yala
82.6 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
92.59 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ...
Private Bedroom on Paradise San Blas Island
Isla Yansailadup Narganá Guna Yala
91.86 km from city center
Stay at this guesthouse in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Museum of the ...
San Blas Private Oceanfront Cabin
C5W9 4M Nusatupo Narganá Guna Yala
79.62 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge).
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Sun, Mar 22 - Mon, Mar 23
MIA
Miami Intl.
PTY
Tocumen Intl.
$318 Roundtrip, found 19 hours ago
$318
Roundtrip
found 19 hours ago
Thu, May 21 - Sun, May 31
MIA
Miami Intl.
PTY
Tocumen Intl.
$365 Roundtrip, found 1 day ago
$365
Roundtrip
found 1 day ago
Mon, May 18 - Thu, May 28
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$370 Roundtrip, found 1 day ago
$370
Roundtrip
found 1 day ago
Fri, May 15 - Fri, Jun 5
MIA
Miami Intl.
PTY
Tocumen Intl.
$374 Roundtrip, found 1 day ago
$374
Roundtrip
found 1 day ago
Wed, May 20 - Wed, May 27
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$475 Roundtrip, found 1 day ago
$475
Roundtrip
found 1 day ago