Eastern Panama Vacation Packages for 2026
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Eastern Panama Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Bella Vista
Price was $1,248, price is now $975 per person
$975
per person
Jun 26 - Jun 30
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Price was $1,682, price is now $1,250 per person
$1,250
per person
Jun 26 - Jun 30
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Megapolis Hotel Panamá
San Francisco
Price was $1,460, price is now $1,115 per person
$1,115
per person
Jun 26 - Jun 30
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Sofitel Legend Casco Viejo, Panama City
Casco Viejo
Price was $1,484, price is now $1,242 per person
$1,242
per person
Jun 26 - Jun 30
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
Price was $1,358, price is now $1,137 per person
$1,137
per person
Jun 26 - Jun 30
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Multiplaza Pacific Mall and Avenida Balboa are located nearby.
Las Americas Golden Tower Panama
San Francisco
Price was $1,184, price is now $992 per person
$992
per person
Jun 26 - Jun 30
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
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See all available trips from Columbus to Eastern Panama
View all tripsTop Hotel Deals
Ciel y Miel
Caillle Principale Cacique Provincia de Colón
164.99 km from city center
Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
92.59 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ...
HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
160.33 km from city center
Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National ...
Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
98.19 km from city center
Book a stay at this beach property in San Blas Islands. Enjoy free breakfast, free WiFi, and a beach locale. Popular attractions Porvenir Museum and Isla Chichime ...
Ordovician Beach Resort
Isla Grande Isla Grande Colon
160.42 km from city center
Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park ...
Konsenda San Blas
Llano Cartí Km 11 El Llano Panamá Province
86.7 km from city center
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
San Blas Private Oceanfront Cabin
C5W9 4M Nusatupo Narganá Guna Yala
79.62 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge).
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
161.23 km from city center
Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ...
Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
160.23 km from city center
Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ...
Discovery Gunayar
Archipiélago de San Blas Narganá Guna Yala
86.38 km from city center
Book a stay at this beach lodge in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime and Isla ...
San Blas Tour Aridub
Urgandi, Guna Yala, Panamá Narganá Guna Yala
80.42 km from city center
Book a stay at this beach cabin in Narganá. Enjoy beach cabanas (surcharge), a beach shuttle (surcharge), and daily housekeeping.
Private Bedroom on Paradise San Blas Island
Isla Yansailadup Narganá Guna Yala
91.86 km from city center
Stay at this guesthouse in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Museum of the ...
San Blas Private Beach Cabin
Nusatupo Narganá Guna Yala
82.6 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Jul 1 - Sun, Jul 5
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$250 Roundtrip, found 11 hours ago
$250
Roundtrip
found 11 hours ago
Wed, Jul 1 - Sun, Jul 5
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$275 Roundtrip, found 11 hours ago
$275
Roundtrip
found 11 hours ago
Sun, May 10 - Mon, May 18
MIA
Miami Intl.
PTY
Tocumen Intl.
$473 Roundtrip, found 2 days ago
$473
Roundtrip
found 2 days ago
Tue, Jul 28 - Sat, Aug 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$551 Roundtrip, found 1 day ago
$551
Roundtrip
found 1 day ago
Tue, Jul 28 - Sat, Aug 1
MIA
Miami Intl.
PTY
Tocumen Intl.
$675 Roundtrip, found 1 day ago
$675
Roundtrip
found 1 day ago