Eastern Panama Vacation Packages for 2026

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Eastern Panama Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Bella Vista
$1,043
per person
Dec 6 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Perfect location and clean

Reviewed on Oct 22, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
$1,487
per person
Dec 6 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
Save 100% on your flight
$1,446
per person
Dec 6 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Property was clean and nice, breakfast was excellent.

Reviewed on Oct 20, 2026

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Tocumen Airport
$1,063
per person
Dec 6 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
W Panama

W Panama

Bella Vista
$1,225
per person
Dec 6 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Hyatt Regency Panama City

Hyatt Regency Panama City

Bella Vista
$1,233
per person
Dec 6 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
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Top Hotel Deals

Ordovician Beach Resort

Ordovician Beach Resort

Isla Grande Isla Grande Colon
160.42 km from city center
Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park ...
Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island Narganá Guna Yala
92.59 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ...
san blas luxury tour

san blas luxury tour

guna yala Nusatupo Guna Yala
79.62 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, free WiFi, and a private beach.
Ciel y Miel

Ciel y Miel

Caillle Principale Cacique Provincia de Colón
164.99 km from city center
Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
Ranchos de Chalia

Ranchos de Chalia

Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
161.23 km from city center
Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ...
Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS

El Porvenir Narganá Guna Yala
98.19 km from city center
Stay at this cruise ship in San Blas Islands. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Porvenir Museum and Isla Chichime ...
Konsenda San Blas

Konsenda San Blas

Llano Cartí Km 11 El Llano Panamá Province
86.7 km from city center
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
Private Bedroom on Paradise San Blas Island

Private Bedroom on Paradise San Blas Island

Isla Yansailadup Narganá Guna Yala
91.86 km from city center
Stay at this guesthouse in Narganá. Enjoy free breakfast, an airport shuttle (surcharge), and a picnic area. Popular attractions Isla Diablo and Museum of the ...
San Blas Tour Aridub

San Blas Tour Aridub

Urgandi, Guna Yala, Panamá Narganá Guna Yala
80.42 km from city center
Book a stay at this beach cabin in Narganá. Enjoy beach cabanas (surcharge), a beach shuttle (surcharge), and daily housekeeping.
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
160.33 km from city center
Stay at this hotel in Isla Grande. Enjoy free breakfast, onsite spa services, and daily housekeeping. Popular attractions Isla Mamey and Portobelo National Park ...
San Blas Private Beach Cabin

San Blas Private Beach Cabin

Nusatupo Narganá Guna Yala
82.6 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
Private Over-Water Cabins on San Blas Island

Private Over-Water Cabins on San Blas Island

C5W9 4M Nusatupo Narganá
88.56 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
San Blas Private Oceanfront Cabin

San Blas Private Oceanfront Cabin

C5W9 4M Nusatupo Narganá Guna Yala
79.62 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge).
Private wood Cabins on San Blas island - private bathroom

Private wood Cabins on San Blas island - private bathroom

Wailidup Island Narganá Guna Yala
93.08 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and a marina. Popular attractions Isla Chichime and Isla Diablo are located ...
Discovery Gunayar

Discovery Gunayar

Archipiélago de San Blas Narganá Guna Yala
86.38 km from city center
Stay at this lodge in Narganá. Enjoy free breakfast, an airport shuttle (surcharge), and housekeeping. Popular attractions Isla Chichime and Isla Diablo are ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, Oct 29 - Fri, Oct 30
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264
Roundtrip
found 3 days ago
Select Copa flight, departing Thu, Oct 29 from Juan Santamaría Intl. to Tocumen Intl., returning Fri, Oct 30, priced at $264 found 3 days ago
avianca
United
Wed, Jan 6 - Sat, Jan 23
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$557
Roundtrip
found 5 days ago
Select United flight, departing Wed, Jan 6 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Sat, Jan 23, priced at $557 found 5 days ago
American Airlines
Delta
Thu, Jan 21 - Tue, Jan 26
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$755
Roundtrip
found 21 hours ago
Select Delta flight, departing Thu, Jan 21 from John F. Kennedy Intl. to Tocumen Intl., returning Tue, Jan 26, priced at $755 found 21 hours ago