Eastern Panama Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Eastern Panama Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City
San Francisco
Price was $1,266, price is now $934 per person
$934
per person
Sep 7 - Sep 12
just found
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $1,987, price is now $1,070 per person
$1,070
per person
Sep 7 - Sep 12
just found
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hotel was excellent with very helpful staff & Anne ties. Location was excellent for touring the area
Reviewed on Jul 21, 2026
Megapolis Hotel Panamá
San Francisco
Save 100% on your flight
Price was $1,715, price is now $1,043 per person
$1,043
per person
Sep 21 - Sep 26
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
I stayed here three days and it was awesome. The entire environment was clean and smells fresh. The staffs are lovely and helpful. The breakfast has lots of food, fruit and juice to choose from. Taxis are available at the entrance
Reviewed on Jul 21, 2026
Riande Aeropuerto Hotel & Casino
Price was $1,379, price is now $980 per person
$980
per person
Sep 7 - Sep 12
just found
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Hotel Riu Plaza Panama
Bella Vista
Price was $1,395, price is now $1,021 per person
$1,021
per person
Sep 7 - Sep 12
just found
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
It’s amazing please. Thanks
Reviewed on Jul 21, 2026
Hyatt Regency Panama City
Bella Vista
Price was $1,378, price is now $1,065 per person
$1,065
per person
Sep 7 - Sep 12
just found
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Love it
Reviewed on Jul 21, 2026
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See all available trips from Columbus to Eastern Panama
View all tripsTop Hotel Deals
Ordovician Beach Resort
Isla Grande Isla Grande Colon
160.42 km from city center
Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park ...
san blas luxury tour
guna yala Nusatupo Guna Yala
79.62 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, free WiFi, and a private beach.
Ciel y Miel
Caillle Principale Cacique Provincia de Colón
164.99 km from city center
Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
98.19 km from city center
Book a stay at this beach cruise ship in San Blas Islands. Enjoy free breakfast, free WiFi, and a beach locale. Popular attractions Porvenir Museum and Isla ...
HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
160.33 km from city center
Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National ...
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
161.23 km from city center
Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ...
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
92.59 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ...
Private Bedroom on Paradise San Blas Island
Isla Yansailadup Narganá Guna Yala
91.86 km from city center
Stay at this guesthouse in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Museum of the ...
Konsenda San Blas
Llano Cartí Km 11 El Llano Panamá Province
86.7 km from city center
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
Discovery Gunayar
Archipiélago de San Blas Narganá Guna Yala
86.38 km from city center
Book a stay at this beach lodge in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime and Isla ...
San Blas Tour Aridub
Urgandi, Guna Yala, Panamá Narganá Guna Yala
80.42 km from city center
Book a stay at this beach cabin in Narganá. Enjoy beach cabanas (surcharge), a beach shuttle (surcharge), and daily housekeeping.
San Blas Private Oceanfront Cabin
C5W9 4M Nusatupo Narganá Guna Yala
79.62 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge).
San Blas Private Beach Cabin
Nusatupo Narganá Guna Yala
82.6 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Mon, Jan 25 - Tue, Jan 26
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264 Roundtrip, found 22 hours ago
$264
Roundtrip
found 22 hours ago
Mon, Jan 25 - Tue, Jan 26
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$290 Roundtrip, found 22 hours ago
$290
Roundtrip
found 22 hours ago
Sun, Sep 6 - Sat, Sep 19
MIA
Miami Intl.
PTY
Tocumen Intl.
$416 Roundtrip, found 1 day ago
$416
Roundtrip
found 1 day ago
Fri, Sep 25 - Sun, Sep 27
MIA
Miami Intl.
PTY
Tocumen Intl.
$431 Roundtrip, found 6 days ago
$431
Roundtrip
found 6 days ago
Mon, Sep 21 - Sun, Sep 27
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$636 Roundtrip, found 1 day ago
$636
Roundtrip
found 1 day ago