Central Missouri Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Top Hotel Deals

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw, Columbia, MO
68.33 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St, Columbia, MO
70.61 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive, Osage Beach, MO
30.41 km from city center
Stay at this 3-star spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
Capitol Plaza Hotel Jefferson City

Capitol Plaza Hotel Jefferson City

3.5 out of 5
Jefferson City 415 W. McCarty St, Jefferson City, MO
47.51 km from city center
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd, Columbia, MO
64.89 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
70.7 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

2.5 out of 5
2904 Clark Lane, Columbia, MO
70.81 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct, Columbia, MO
70.41 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW, Columbia, MO
68.32 km from city center
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
Ramada by Wyndham Columbia

Ramada by Wyndham Columbia

2.5 out of 5
901 Conley Rd, Columbia, MO
70.51 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Columbia East by IHG

Holiday Inn Columbia East by IHG

3 out of 5
915 Port Way, Columbia, MO
72.05 km from city center
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy, Osage Beach, MO
30.1 km from city center
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
Osage Village Inn

Osage Village Inn

2.5 out of 5
4616 Osage Beach Parkway, Osage Beach, MO
28.6 km from city center
Stay at this hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

2.5 out of 5
1402 Cinnamon Hill Lane, Columbia, MO
68.04 km from city center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Rolla

Days Inn by Wyndham Rolla

2.5 out of 5
2006 N Bishop Ave, Rolla, MO
93.02 km from city center
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Don't see what you're looking for?
See all available properties in Central Missouri
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jul 1 - Tue, Jul 8
AUS
Austin-Bergstrom Intl.
COU
Columbia Regional
$402 Roundtrip, found 20 hours ago
$402
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jul 1 from Austin-Bergstrom Intl. to Columbia Regional, returning Tue, Jul 8, priced at $402 found 20 hours ago
American Airlines
Tue, Jul 1 - Thu, Jul 10
AUS
Austin-Bergstrom Intl.
COU
Columbia Regional
$449 Roundtrip, found 20 hours ago
$449
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jul 1 from Austin-Bergstrom Intl. to Columbia Regional, returning Thu, Jul 10, priced at $449 found 20 hours ago
American Airlines
Fri, Jul 4 - Tue, Jul 8
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$450 Roundtrip, found 20 hours ago
$450
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Fri, Jul 4 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Jul 8, priced at $450 found 20 hours ago
American Airlines
Tue, Jul 8 - Sun, Jul 13
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$483 Roundtrip, found 20 hours ago
$483
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jul 8 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sun, Jul 13, priced at $483 found 20 hours ago