Central Missouri Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
Lodge Of Four Seasons Golf Resort, Marina & Spa
315 Four Seasons Dr. Lake Ozark MO
Book a stay at this beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Best Western Plus Columbia Inn
2904 Clark Lane Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Plaza Hotel Columbia East
3100 Interstate 70 Dr. SE Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Margaritaville Lake Resort Lake of the Ozarks
494 Tan Tar A Drive Osage Beach MO
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
Capitol Plaza Hotel Jefferson City
Jefferson City 415 W. McCarty St Jefferson City MO
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff ...
Days Inn by Wyndham Rolla
2006 N Bishop Ave Rolla MO
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Hotel Blu
3402 Interstate 70 Dr SE Columbia MO
Stay at this hotel in Columbia. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Stephens Lake Park and Liddell Dam are located ...
Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Inn at Grand Glaize
5142 Osage Beach Pkwy Osage Beach MO
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
Baymont by Wyndham Ft. Leonard/Saint Robert
139 Carmel Valley Way St. Robert MO
Book a stay at this business-friendly hotel in St. Robert. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Baymont by Wyndham Rolla
1801 Martin Springs Dr Rolla MO
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Days Inn by Wyndham Osage Beach Lake of the Ozarks
4755 Osage Beach Parkway Osage Beach MO
Book a stay at this business-friendly hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Bagnell Dam and Osage Beach ...
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See all available properties in Central Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Fri, Oct 2 - Thu, Oct 8
DFW
Dallas-Fort Worth Intl.
COU
Columbia Regional
$525
Roundtrip
found 3 days ago
Fri, Oct 2 - Thu, Oct 8
DFW
Dallas-Fort Worth Intl.
COU
Columbia Regional
$534
Roundtrip
found 3 days ago
Fri, Oct 2 - Thu, Oct 8
DFW
Dallas-Fort Worth Intl.
COU
Columbia Regional
$544
Roundtrip
found 3 days ago
Fri, Oct 2 - Thu, Oct 8
DFW
Dallas-Fort Worth Intl.
COU
Columbia Regional
$548
Roundtrip
found 3 days ago
Best neighborhoods in Central Missouri
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All accommodation types in Central Missouri
More Types of Hotels
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- All-inclusive Hotel in Central Missouri