2025 4 Star Hotels in Downtown Syracuse

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Featured Downtown Syracuse 4 Star Hotels

Marriott Syracuse Downtown

Marriott Syracuse Downtown

4 out of 5
100 East Onondaga Street, Syracuse, NY
Fully refundableReserve now, pay when you stay
Marriott Syracuse Downtown
DoubleTree by Hilton Hotel Syracuse

DoubleTree by Hilton Hotel Syracuse

4 out of 5
6301 Route 298, East Syracuse, NY
Fully refundableReserve now, pay when you stay
DoubleTree by Hilton Hotel Syracuse
The Brewster Inn

The Brewster Inn

4 out of 5
6 Ledyard Avenue, Cazenovia, NY
Fully refundableReserve now, pay when you stay
The Brewster Inn
Mirbeau Inn and Spa

Mirbeau Inn and Spa

4 out of 5
851 West Genesee Street, Skaneateles, NY
Fully refundableReserve now, pay when you stay
Mirbeau Inn and Spa
Skaneateles Fields Resort & Spa, Curio Collection By Hilton

Skaneateles Fields Resort & Spa, Curio Collection By Hilton

4 out of 5
1000 Mottville Road, Skaneateles, NY
Fully refundableReserve now, pay when you stay
Skaneateles Fields Resort & Spa, Curio Collection By Hilton
The Bond 1835

The Bond 1835

4 out of 5
2498 E Lake Rd, Skaneateles, NY
The Bond 1835
Comfort Inn & Suites Airport

Comfort Inn & Suites Airport

4 out of 5
6701 Buckley Rd, I-90 & I-81, North Syracuse, NY
Comfort Inn & Suites Airport
See all 557 properties in Downtown Syracuse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.