Clayton 4 Star Hotels In 2026

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Featured Clayton 4 Star Hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
Hyatt Regency St. Louis at The Arch
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
Moonrise Hotel
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
The Royal Sonesta Chase Park Plaza St. Louis
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4 out of 5
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
Hilton St. Louis Frontenac
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4 out of 5
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
St. Louis Union Station Hotel, Curio Collection by Hilton
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
Renaissance St. Louis Airport Hotel
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Live by Loews - St.Louis
The Westin St. Louis

The Westin St. Louis

4.5 out of 5
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
The Westin St. Louis
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
21C Museum Hotel St Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.