Santa Clara Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
8.04 km from Santa Clara
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
8.38 km from Santa Clara
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
10.16 km from Santa Clara
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
19.45 km from Santa Clara
Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall ...
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
6.62 km from Santa Clara
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Megapolis Hotel Panamá
Avenida Balboa Panama City
8.19 km from Santa Clara
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Principe Hotel and Suites
Via Argentina Panama City Panama
7.79 km from Santa Clara
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
Avenida Peru Y Calle 30 Panama City Panama Province
10.38 km from Santa Clara
Stay at this hotel in Panama City. Enjoy free breakfast, a 24-hour front desk, and 4 meeting rooms. Popular attractions Albrook Shopping Mall and Cinta Costera ...
Riande Aeropuerto Hotel & Casino
Vía Tocumen Tocumen Panama
8.69 km from Santa Clara
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
The Executive Hotel
Calle 52 Panama City Panama
8.41 km from Santa Clara
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
8.13 km from Santa Clara
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
8.3 km from Santa Clara
Book a stay at this spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
6.08 km from Santa Clara
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Mon, Dec 7 - Wed, Dec 23
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$762 Roundtrip, found 2 days ago
$762
Roundtrip
found 2 days ago
Thu, Jan 21 - Tue, Jan 26
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$777 Roundtrip, just found
$777
Roundtrip
just found
Mon, Dec 7 - Wed, Dec 23
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$785 Roundtrip, found 2 days ago
$785
Roundtrip
found 2 days ago
Thu, Jan 21 - Tue, Jan 26
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$798 Roundtrip, just found
$798
Roundtrip
just found
Thu, Jan 21 - Tue, Jan 26
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$808 Roundtrip, just found
$808
Roundtrip
just found