Upstate South Carolina Hotel Rooms at the Independent

Featured Upstate South Carolina Independent Hotels

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Free Cancellation
Reserve now, pay when you stay
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Free Cancellation
Reserve now, pay when you stay
Greenville Inn and Suites

Greenville Inn and Suites

2.5 out of 5
1314 S Pleasantburg Dr Greenville SC
Free Cancellation
Reserve now, pay when you stay
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
Free Cancellation
Reserve now, pay when you stay
Horizon Inn & Suites

Horizon Inn & Suites

2 out of 5
3025 N Main Street Anderson SC
The Abernathy of Clemson

The Abernathy of Clemson

4 out of 5
157 Old Greenville Hwy Clemson SC
Free Cancellation
Reserve now, pay when you stay
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street Clemson SC
Free Cancellation
Reserve now, pay when you stay
Greenville Pelham Inn by IHG

Greenville Pelham Inn by IHG

2 out of 5
20 Interstate Ct Greenville SC
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.