Upstate South Carolina Hotel Rooms at the Best Western

Featured Upstate South Carolina Best Western Hotels

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road, Greenville, SC
Free Cancellation
Reserve now, pay when you stay
Best Western Spartanburg Northwest

Best Western Spartanburg Northwest

3 out of 5
110 Mobile Dr, Spartanburg, SC
Best Western Travelers Rest Greenville

Best Western Travelers Rest Greenville

2.5 out of 5
110 Hawkins Rd, Travelers Rest, SC
Free Cancellation
Reserve now, pay when you stay
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123, Seneca, SC
Free Cancellation
Reserve now, pay when you stay
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.