South Jefferson Vacation Packages for 2026

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Top Hotel Deals

SpringHill Suites by Marriott Roanoke

SpringHill Suites by Marriott Roanoke

3 out of 5
301 Reserve Ave SW Roanoke VA
0.4 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in ...
Baymont by Wyndham Salem Roanoke Area

Baymont by Wyndham Salem Roanoke Area

2.5 out of 5
179 Sheraton Drive Salem VA
10.59 km from South Jefferson
Book a stay at this business-friendly motel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
The Liberty Trust

The Liberty Trust

4 out of 5
101 S Jefferson St, Roanoke VA 24011 Roanoke VA
1.54 km from South Jefferson
Book a stay at this luxury hotel in Roanoke. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
Spark by Hilton Roanoke Airport

Spark by Hilton Roanoke Airport

3 out of 5
3695 Thirlane Rd Nw Roanoke VA
6.54 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and a free airport shuttle. Popular attractions Valley View Mall and ...
Hyatt Place Roanoke Airport/Valley View Mall

Hyatt Place Roanoke Airport/Valley View Mall

3 out of 5
5040 Valley View Blvd North Roanoke VA
6.06 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
avid hotel Salem by IHG

avid hotel Salem by IHG

2.5 out of 5
501 WILDWOOD ROAD Salem VA
14.73 km from South Jefferson
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Spark by Hilton Roanoke Civic Center

Spark by Hilton Roanoke Civic Center

2.5 out of 5
815 Gainsboro Rd Nw Roanoke VA
2.58 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 

Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 

4 out of 5
110 Shenandoah Ave Ne Roanoke VA
1.81 km from South Jefferson
Book a stay at this luxury hotel in Roanoke. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition ...
Country Inn & Suites by Radisson, Roanoke, VA

Country Inn & Suites by Radisson, Roanoke, VA

3 out of 5
7860 Plantation Rd Roanoke VA
10.86 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn & Suites by Wyndham Roanoke Salem

La Quinta Inn & Suites by Wyndham Roanoke Salem

3 out of 5
140 Sheraton Dr Salem VA
10.58 km from South Jefferson
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Comfort Inn & Suites Troutville-Roanoke North

Comfort Inn & Suites Troutville-Roanoke North

2.5 out of 5
3231 Lee Highway South Troutville VA
15.42 km from South Jefferson
Book a stay at this business-friendly hotel in Troutville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Springhill Suites By Marriott Roanoke North

Springhill Suites By Marriott Roanoke North

4 out of 5
8171 Gander Way Roanoke VA
11.25 km from South Jefferson
Stay at this hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Eleanor ...
Holiday Inn Express & Suites Roanoke – Civic Center by IHG

Holiday Inn Express & Suites Roanoke – Civic Center by IHG

2.5 out of 5
1303 Williamson Road Roanoke VA
2.92 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
The Promissory Hotel

The Promissory Hotel

2 out of 5
201 S Jefferson St Roanoke VA
1.47 km from South Jefferson
Stay at this hotel in Roanoke. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Popular attractions Center in the Square and Roanoke Pinball ...
Fairfield Inn & Suites by Marriott Roanoke Salem

Fairfield Inn & Suites by Marriott Roanoke Salem

3 out of 5
121 Sheraton Drive Salem VA
10.57 km from South Jefferson
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jul 28 - Tue, Aug 11
PHX
Sky Harbor Intl.
ROA
Roanoke Regional
$359 Roundtrip, found 6 days ago
$359
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jul 28 from Sky Harbor Intl. to Roanoke Regional, returning Tue, Aug 11, priced at $359 found 6 days ago
Delta
Tue, Jul 28 - Tue, Aug 11
PHX
Sky Harbor Intl.
ROA
Roanoke Regional
$359 Roundtrip, found 6 days ago
$359
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Jul 28 from Sky Harbor Intl. to Roanoke Regional, returning Tue, Aug 11, priced at $359 found 6 days ago
Delta
Wed, Jul 1 - Fri, Jul 3
ATL
Hartsfield-Jackson Atlanta Intl.
ROA
Roanoke Regional
$359 Roundtrip, found 3 days ago
$359
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Jul 1 from Hartsfield-Jackson Atlanta Intl. to Roanoke Regional, returning Fri, Jul 3, priced at $359 found 3 days ago
United
Tue, Jul 28 - Tue, Aug 11
PHX
Sky Harbor Intl.
ROA
Roanoke Regional
$393 Roundtrip, found 6 days ago
$393
Roundtrip
found 6 days ago
Select United flight, departing Tue, Jul 28 from Sky Harbor Intl. to Roanoke Regional, returning Tue, Aug 11, priced at $393 found 6 days ago