South Jefferson Vacation Packages for 2026

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Top Hotel Deals

SpringHill Suites by Marriott Roanoke

SpringHill Suites by Marriott Roanoke

3 out of 5
301 Reserve Ave SW Roanoke VA
0.4 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff in ...
Baymont by Wyndham Salem Roanoke Area

Baymont by Wyndham Salem Roanoke Area

2.5 out of 5
179 Sheraton Drive Salem VA
10.59 km from South Jefferson
Book a stay at this business-friendly motel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Country Inn & Suites by Radisson, Roanoke, VA

Country Inn & Suites by Radisson, Roanoke, VA

3 out of 5
7860 Plantation Rd Roanoke VA
10.86 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 

Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 

4 out of 5
110 Shenandoah Ave Ne Roanoke VA
1.81 km from South Jefferson
Book a stay at this luxury hotel in Roanoke. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition ...
The Liberty Trust

The Liberty Trust

4 out of 5
101 S Jefferson St, Roanoke VA 24011 Roanoke VA
1.54 km from South Jefferson
Book a stay at this luxury hotel in Roanoke. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
avid hotel Salem by IHG

avid hotel Salem by IHG

2.5 out of 5
501 WILDWOOD ROAD Salem VA
14.73 km from South Jefferson
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
La Quinta Inn & Suites by Wyndham Roanoke Salem

La Quinta Inn & Suites by Wyndham Roanoke Salem

3 out of 5
140 Sheraton Dr Salem VA
10.58 km from South Jefferson
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hyatt Place Roanoke Airport/Valley View Mall

Hyatt Place Roanoke Airport/Valley View Mall

3 out of 5
5040 Valley View Blvd North Roanoke VA
6.06 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Spark by Hilton Roanoke Civic Center

Spark by Hilton Roanoke Civic Center

2.5 out of 5
815 Gainsboro Rd Nw Roanoke VA
2.58 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Springhill Suites By Marriott Roanoke North

Springhill Suites By Marriott Roanoke North

4 out of 5
8171 Gander Way Roanoke VA
11.25 km from South Jefferson
Stay at this hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Berglund ...
Comfort Inn & Suites Troutville-Roanoke North

Comfort Inn & Suites Troutville-Roanoke North

2.5 out of 5
3231 Lee Highway South Troutville VA
15.42 km from South Jefferson
Book a stay at this business-friendly hotel in Troutville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Holiday Inn Express & Suites Roanoke – Civic Center by IHG

Holiday Inn Express & Suites Roanoke – Civic Center by IHG

2.5 out of 5
1303 Williamson Road Roanoke VA
2.92 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Roanoke-Tanglewood-Rt 419&i581 by IHG

Holiday Inn Roanoke-Tanglewood-Rt 419&i581 by IHG

3 out of 5
4468 Starkey Road Roanoke VA
5.21 km from South Jefferson
Book a stay at this business-friendly hotel in Roanoke. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
The Promissory Hotel

The Promissory Hotel

2 out of 5
201 S Jefferson St Roanoke VA
1.47 km from South Jefferson
Stay at this hotel in Roanoke. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Popular attractions Berglund Center and Center in the Square ...
The Lofts at Downtown Salem

The Lofts at Downtown Salem

3.5 out of 5
10 W Main St Salem VA
10.96 km from South Jefferson
Stay at this hotel in Salem. Enjoy free WiFi, laundry facilities, and cable TV channels. Popular attractions Longwood Park and Salem Museum are located ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Aug 13 - Sun, Aug 16
EWR
Newark Liberty Intl. Airport
ROA
Roanoke Regional
$299 Roundtrip, found 6 days ago
$299
Roundtrip
found 6 days ago
Select United flight, departing Thu, Aug 13 from Newark Liberty Intl. Airport to Roanoke Regional, returning Sun, Aug 16, priced at $299 found 6 days ago
Delta
Wed, Aug 12 - Tue, Aug 18
EWR
Newark Liberty Intl. Airport
ROA
Roanoke Regional
$314 Roundtrip, found 6 days ago
$314
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Aug 12 from Newark Liberty Intl. Airport to Roanoke Regional, returning Tue, Aug 18, priced at $314 found 6 days ago
Delta
Wed, Aug 12 - Sun, Aug 16
EWR
Newark Liberty Intl. Airport
ROA
Roanoke Regional
$329 Roundtrip, found 6 days ago
$329
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Aug 12 from Newark Liberty Intl. Airport to Roanoke Regional, returning Sun, Aug 16, priced at $329 found 6 days ago
American Airlines
Thu, Aug 13 - Sun, Aug 16
EWR
Newark Liberty Intl. Airport
ROA
Roanoke Regional
$428 Roundtrip, found 6 days ago
$428
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Aug 13 from Newark Liberty Intl. Airport to Roanoke Regional, returning Sun, Aug 16, priced at $428 found 6 days ago