Santa Rosa Vacations

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

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Top Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
30.22 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
30.82 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
30.84 km from city center
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
30.43 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
31.26 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
29.48 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
29.42 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
29.77 km from city center
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
31.67 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
30.19 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
30.91 km from city center
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
30.86 km from city center
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
30.01 km from city center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons Panama City Panama
29.19 km from city center
Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 out of 5
Calle 52 and Ricardo Arias Panama City
29.96 km from city center
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Avenida ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sun, Dec 28 - Thu, Jan 1
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$230 Roundtrip, found 5 days ago
$230
Roundtrip
found 5 days ago
Select Copa flight, departing Sun, Dec 28 from Juan Santamaría Intl. to Tocumen Intl., returning Thu, Jan 1, priced at $230 found 5 days ago
avianca
Sat, Dec 27 - Mon, Dec 29
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$263 Roundtrip, found 5 days ago
$263
Roundtrip
found 5 days ago
Select avianca flight, departing Sat, Dec 27 from Juan Santamaría Intl. to Tocumen Intl., returning Mon, Dec 29, priced at $263 found 5 days ago
United
Tue, Jan 13 - Tue, Jan 20
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$562 Roundtrip, found 3 days ago
$562
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jan 13 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Tue, Jan 20, priced at $562 found 3 days ago
American Airlines
Tue, Mar 17 - Fri, Mar 20
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$583 Roundtrip, found 1 day ago
$583
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 17 from Newark Liberty Intl. Airport to Tocumen Intl., returning Fri, Mar 20, priced at $583 found 1 day ago
Delta
Sat, Mar 14 - Wed, Mar 25
LAX
Los Angeles Intl.
PTY
Tocumen Intl.
$644 Roundtrip, found 1 day ago
$644
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Mar 14 from Los Angeles Intl. to Tocumen Intl., returning Wed, Mar 25, priced at $644 found 1 day ago