San Francisco Vacations

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San Francisco Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City

Decapolis Hotel Panama City

San Francisco
Save 100% on your flight
$942
per person
Sep 13 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
$1,123
per person
Sep 13 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Nice hotel. Great location. Good breakfast. Our only complaint is about noise. The hotel has live music in the atrium from early in the morning until about 10 pm. Our room, along with many others, had windows facing into the atrium, and the noise from the music, and sometimes large tour groups at breakfast, may disturb your sleep.

Reviewed on Aug 10, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
Save 100% on your flight
$1,081
per person
Oct 23 - Oct 29
found 1 day ago
Roundtrip non-stop flight included
Orlando (MCO) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
The room smelled like humid, and it was actually very humid, the walls in the bathroom where super dirty, housekeeping came in 2 times in our 6 night stay. We had to change room because of the smell.

Reviewed on Aug 11, 2026

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Save 100% on your flight
$974
per person
Sep 13 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Buena alternativa para descansar y a pocos minutos del aeropuerto.

Reviewed on Aug 9, 2026

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Bella Vista
Save 100% on your flight
$1,006
per person
Sep 13 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Hyatt Regency Panama City

Hyatt Regency Panama City

Bella Vista
Save 100% on your flight
$1,170
per person
Sep 13 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Limpio, personal servicial

Reviewed on Aug 11, 2026

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Top Hotel Deals

Hotel Gran David

Hotel Gran David

Vía Interamericana Santiago Veraguas
15.36 km from city center
Stay at this hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
Hotel Mykonos Panama

Hotel Mykonos Panama

Panamerican Highway Nuevo Santiago Veraguas
16.8 km from city center
Book a stay at this spa hotel in Nuevo Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Plaza Banconal and Omar Torrijos Herrera ...
HOTEL VISTA LAGO

HOTEL VISTA LAGO

Rincón Largo La Pena Santiago de Veraguas
12.27 km from city center
Stay at this hotel in La Pena. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Acuatico Italia Guadalupe Panama and Omar Torrijos ...
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

Vía interamericana Nuevo Santiago Provincia de Veraguas
15.17 km from city center
Book a stay at this business-friendly hotel in Nuevo Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Plaza Banconal and Omar ...
Hotel Anachoreo

Hotel Anachoreo

Calle Chinita Santa Fe Veraguas Province
32.59 km from city center
Stay at this B&B in Santa Fe. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Town Square and Mercado are located nearby.
Hotel Galería

Hotel Galería

Vía Interamericana Santiago, Km 232.88 Nuevo Santiago
15.67 km from city center
Book a stay at this business-friendly hotel in Nuevo Santiago. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Plaza Banconal and Omar ...
Hotel La Hacienda

Hotel La Hacienda

Via Interamericana Rodrigo Luque Veraguas
13.22 km from city center
Book a stay at this family-friendly hotel in Rodrigo Luque. Enjoy free WiFi, free parking, and a casino. Popular attractions Parque Acuatico Italia Guadalupe ...
La Qhia Eco Retreat

La Qhia Eco Retreat

Barriada el Cerro A 100 Mts De Santa Fe Veraguas
32.46 km from city center
Stay at this hostal in Santa Fe. Enjoy free parking, breakfast (surcharge), and onsite spa services. Popular attractions Town Square and Mercado are located ...
Hotel Plaza

Hotel Plaza

Interamericana Nuevo Santiago Veraguas
16.26 km from city center
Book a stay at this family-friendly hotel in Nuevo Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Plaza Banconal and ...
HOTEL CORPORATIVO PLAZA COROTÚ

HOTEL CORPORATIVO PLAZA COROTÚ

Carr. Panamericana Santiago Provincia de Veraguas
15.97 km from city center
Stay at this hotel in Santiago. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Plaza Banconal and Omar Torrijos Herrera Stadium ...
HOTEL PLAZA COROTÚ

HOTEL PLAZA COROTÚ

Carr. Panamericana Santiago Provincia de Veraguas
15.97 km from city center
Stay at this hotel in Santiago. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Popular attractions Plaza Banconal and Omar Torrijos Herrera Stadium ...
Rainforest Yasmin Hotel

Rainforest Yasmin Hotel

Veraguas Santa Fe Provincia de Veraguas
32.37 km from city center
Stay at this hotel in Santa Fe. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Town Square and Orchid House are located ...
Hostal Travelers

Hostal Travelers

Santiago de Veraguas Santiago Veraguas
15 km from city center
Stay at this hostal in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Omar Torrijos Herrera Stadium and Plaza Banconal ...
Hostal Brisas Calobreñas

Hostal Brisas Calobreñas

Calobre Calobre Veraguas
17.28 km from city center
Stay at this hostal in Calobre. Enjoy free WiFi, free parking, and breakfast (surcharge).
Black Lion Inn

Black Lion Inn

Vía Interamericana La Mata Veraguas
20.06 km from city center
Stay at this hostal in La Mata. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Los Pozos Termales and Plaza Banconal are located ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.