Cheap 2025 Otay Mesa West Hotels
Photo by Leonardo De Leon
Choose from 6600 Otay Mesa West Hotel Deals
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
19.21 km from Otay Mesa West
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
27.07 km from Otay Mesa West
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.19 km from Otay Mesa West
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Hyatt Regency Mission Bay Spa and Marina
1441 Quivira Rd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
27.22 km from Otay Mesa West
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Embassy Suites by Hilton San Diego Bay Downtown
601 Pacific Hwy, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.44 km from Otay Mesa West
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
Dextro, Little Italy, BW Premier Collection
1617 1st Avenue, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
19.06 km from Otay Mesa West
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Handlery Hotel
950 Hotel Cir N, San Diego, CA
23.14 km from Otay Mesa West
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
17.17 km from Otay Mesa West
Stay at this 4-star spa hotel in San Diego. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
17.95 km from Otay Mesa West
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
Hampton Inn San Diego/Mission Valley
2151 Hotel Circle South, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
23.45 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Sheraton San Diego Resort
1380 Harbor Island Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
21.38 km from Otay Mesa West
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Bay Club Hotel & Marina
2131 Shelter Island Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
22.11 km from Otay Mesa West
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant ...
Best Western Plus Marina Gateway Hotel
800 Bay Marina Dr, National City, CA
Free Cancellation
Reserve now, pay when you stay
10.5 km from Otay Mesa West
Stay at this 3.5-star eco-certified hotel in National City. Enjoy free WiFi, free parking, and a golf course. Our guests praise the pool and the restaurant in ...
The Little Italy Hotel Downtown San Diego
1646 Front St, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
19.15 km from Otay Mesa West
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in our reviews. ...
Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave, Coronado, CA
Free Cancellation
Reserve now, pay when you stay
16.28 km from Otay Mesa West
Stay at this 4-star beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff and the property condition ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa West, San Diego Hotel Guide
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More Otay Mesa West Hotel Deals for Seniors and Members
- Wyndham San Diego Bayside
- The Dana on Mission Bay
- Manchester Grand Hyatt San Diego
- Hyatt Regency Mission Bay Spa and Marina
- Embassy Suites by Hilton San Diego Bay Downtown
- Dextro, Little Italy, BW Premier Collection
- Handlery Hotel
- Hilton San Diego Bayfront
- Marriott Marquis San Diego Marina
- Hampton Inn San Diego/Mission Valley