
Cheap 2026 Otay Mesa West Hotels
Choose from 6936 Otay Mesa West Hotel Deals

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Free Cancellation
Reserve now, pay when you stay
17.51 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...

The Sofia Hotel
150 W Broadway San Diego CA
Free Cancellation
Reserve now, pay when you stay
18.5 km from Otay Mesa West
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...

Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
Free Cancellation
Reserve now, pay when you stay
27.94 km from Otay Mesa West
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Free Cancellation
19.06 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave Coronado CA
Free Cancellation
Reserve now, pay when you stay
16.29 km from Otay Mesa West
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular ...

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
19.21 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...

Best Western Seven Seas
411 Hotel Circle South San Diego CA
Free Cancellation
Reserve now, pay when you stay
22.89 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...

Handlery Hotel
950 Hotel Cir N San Diego CA
Free Cancellation
Reserve now, pay when you stay
23.14 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...

Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
21.38 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...

California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
Free Cancellation
Reserve now, pay when you stay
30.62 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...

Omni San Diego Hotel at the Ballpark
675 L St San Diego CA
Free Cancellation
Reserve now, pay when you stay
17.41 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...

Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
22.93 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...

Hyatt Regency Mission Bay Spa and Marina
1441 Quivira Rd San Diego CA
Free Cancellation
Reserve now, pay when you stay
27.22 km from Otay Mesa West
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...

The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
27.13 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...

Marriott Marquis San Diego Marina
333 W Harbor Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
17.88 km from Otay Mesa West
Book a stay at this family-friendly hotel in San Diego. Enjoy 2 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa West, San Diego Hotel Guide
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