Cheap 2025 Otay Mesa West Hotels
Photo by Leonardo De Leon
Choose from 6491 Otay Mesa West Hotel Deals
Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
17.95 km from Otay Mesa West
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.19 km from Otay Mesa West
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Kings Inn San Diego
1333 Hotel Cir S, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
23.08 km from Otay Mesa West
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
27.07 km from Otay Mesa West
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
Handlery Hotel
950 Hotel Cir N, San Diego, CA
23.14 km from Otay Mesa West
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
DoubleTree by Hilton Hotel San Diego - Mission Valley
7450 Hazard Center Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
23.53 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful ...
Comfort Inn Sea World Area
3880 Greenwood St, San Diego, CA
24.31 km from Otay Mesa West
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Embassy Suites by Hilton San Diego Bay Downtown
601 Pacific Hwy, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.44 km from Otay Mesa West
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
Wyndham Garden San Diego Near SeaWorld
3737 Sports Arena Blvd, San Diego, CA
24.78 km from Otay Mesa West
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
19.21 km from Otay Mesa West
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
1380 Harbor Island Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
21.38 km from Otay Mesa West
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Lafayette Hotel & Club
2223 El Cajon Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
21.31 km from Otay Mesa West
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Hilton San Diego Mission Valley
901 Camino Del Rio S, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
22.79 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
23.94 km from Otay Mesa West
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
17.17 km from Otay Mesa West
Stay at this 4-star spa hotel in San Diego. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa West, San Diego Hotel Guide
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More Otay Mesa West Hotel Deals for Seniors and Members
- Marriott Marquis San Diego Marina
- Manchester Grand Hyatt San Diego
- Kings Inn San Diego
- The Dana on Mission Bay
- Handlery Hotel
- DoubleTree by Hilton Hotel San Diego - Mission Valley
- Comfort Inn Sea World Area
- Embassy Suites by Hilton San Diego Bay Downtown
- Wyndham Garden San Diego Near SeaWorld
- Wyndham San Diego Bayside