Medical Center Vacation Packages for 2026

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Medical Center Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Trumbull and Porter Hotel

Trumbull and Porter Hotel

3.5 out of 5
Corktown
Save 100% on your flight
Price was $1,022, price is now $648 per person
$648
per person
Dec 1 - Dec 9
found 3 hours ago
Roundtrip flight included
Houston (IAH) to Detroit (DTW)
Book a stay at this business-friendly hotel in Detroit. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Little Caesars Arena and Ford Field are located nearby.

Hollywood Casino at Greektown

Hollywood Casino at Greektown

4 out of 5
Downtown Detroit
Save 100% on your flight
Price was $1,073, price is now $801 per person
$801
per person
Dec 1 - Dec 9
found 3 hours ago
Roundtrip flight included
Houston (IAH) to Detroit (DTW)
Book a stay at this business-friendly hotel in Detroit. Enjoy free WiFi, 5 restaurants, and a casino. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Ford Field and Little Caesars Arena are located nearby.
There is thick dust on the closet, and the hotel was out of soap and towels during our stay.

Reviewed on Oct 27, 2026

Hotel Indigo Detroit Downtown by IHG

Hotel Indigo Detroit Downtown by IHG

3.5 out of 5
Downtown Detroit
Save 100% on your flight
Price was $950, price is now $733 per person
$733
per person
Dec 1 - Dec 9
found 3 hours ago
Roundtrip flight included
Houston (IAH) to Detroit (DTW)
Book a stay at this business-friendly hotel in Detroit. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Ford Field and Little Caesars Arena are located nearby.

Hotel Houze Detroit Downtown

Hotel Houze Detroit Downtown

3 out of 5
Downtown Detroit
Save 100% on your flight
Price was $911, price is now $712 per person
$712
per person
Dec 1 - Dec 9
found 3 hours ago
Roundtrip flight included
Houston (IAH) to Detroit (DTW)
Stay at this hotel in Detroit. Enjoy free WiFi, a 24-hour fitness center, and a 24-hour front desk. Popular attractions Ford Field and Little Caesars Arena are located nearby.

Royal Park Hotel

Royal Park Hotel

4 out of 5
Price was $1,523, price is now $1,196 per person
$1,196
per person
Dec 2 - Dec 7
found 1 day ago
Roundtrip flight included
Raleigh (RDU) to Detroit (DTW)
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Rochester Municipal Park and Blackheath Golf Club are located nearby.
Luxury at it most luxurious.

Reviewed on Oct 27, 2026

The Inn on Ferry Street

The Inn on Ferry Street

3.5 out of 5
Cultural Center
Save 100% on your flight
Price was $1,084, price is now $858 per person
$858
per person
Dec 1 - Dec 9
found 3 hours ago
Roundtrip flight included
Houston (IAH) to Detroit (DTW)
Book a stay at this historic hotel in Detroit. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Little Caesars Arena and Ford Field are located nearby.

Don't see what you're looking for?
See all available trips from Columbus to Medical Center
View all trips

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Tue, Dec 1 - Thu, Dec 10
DFW
Dallas-Fort Worth Intl.
DTW
Detroit Metropolitan Wayne County
$79 Roundtrip, found 1 day ago
$79
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Dec 1 from Dallas-Fort Worth Intl. to Detroit Metropolitan Wayne County, returning Thu, Dec 10, priced at $79 found 1 day ago
Delta
Fri, Dec 4 - Sun, Dec 13
DFW
Dallas-Fort Worth Intl.
DTW
Detroit Metropolitan Wayne County
$139 Roundtrip, found 1 day ago
$139
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Dec 4 from Dallas-Fort Worth Intl. to Detroit Metropolitan Wayne County, returning Sun, Dec 13, priced at $139 found 1 day ago
American Airlines
Fri, Dec 4 - Sun, Dec 13
DFW
Dallas-Fort Worth Intl.
DTW
Detroit Metropolitan Wayne County
$157 Roundtrip, found 1 day ago
$157
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Dec 4 from Dallas-Fort Worth Intl. to Detroit Metropolitan Wayne County, returning Sun, Dec 13, priced at $157 found 1 day ago
JetBlue Airways
Thu, Nov 12 - Sun, Nov 15
FLL
Fort Lauderdale - Hollywood Intl.
DTW
Detroit Metropolitan Wayne County
$197 Roundtrip, found 1 day ago
$197
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Thu, Nov 12 from Fort Lauderdale - Hollywood Intl. to Detroit Metropolitan Wayne County, returning Sun, Nov 15, priced at $197 found 1 day ago
United
Thu, Nov 12 - Sun, Nov 15
FLL
Fort Lauderdale - Hollywood Intl.
DTW
Detroit Metropolitan Wayne County
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select United flight, departing Thu, Nov 12 from Fort Lauderdale - Hollywood Intl. to Detroit Metropolitan Wayne County, returning Sun, Nov 15, priced at $217 found 1 day ago