Lake Marion Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Photo by Charles Arcudi
Choose two or more items and save on your trip:

Top Hotel Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
12.54 km from city center
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd, Santee, SC
12.63 km from city center
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
11.89 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
12.48 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2.5 out of 5
2816 Paxville Highway, Manning, SC
24.21 km from city center
Book a stay at this business-friendly hotel in Manning. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Moncks Corner Inn

Moncks Corner Inn

2.5 out of 5
505 Rembert C. Dennis Blvd, Moncks Corner, SC
46.93 km from city center
Book a stay at this business-friendly hotel in Moncks Corner. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
12.72 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway, Santee, SC
12.48 km from city center
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 out of 5
739 Citadel Road, Orangeburg, SC
45.29 km from city center
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
11.93 km from city center
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

2 out of 5
3620 Saint Matthews Rd, Orangeburg, SC
45.43 km from city center
Stay at this motel in Orangeburg. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG

2.5 out of 5
118 Sleep Inn Road, Orangeburg, SC
45.46 km from city center
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg

2.5 out of 5
675 Citadel Rd, Orangeburg, SC
45.13 km from city center
Stay at this hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

2 out of 5
3608 Saint Matthews Rd, Orangeburg, SC
45.52 km from city center
Book a stay at this business-friendly motel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Carolina Inn

Carolina Inn

102 S Hwy 52, Moncks Corner, SC
47.1 km from city center
Stay at this motel in Moncks Corner. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Old Santee Canal State Park and Mepkin Abbey ...
Don't see what you're looking for?
See all available properties in Lake Marion
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.