La Plata Vacations

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Top Hotel Deals

Depot Inn and Suites

Depot Inn and Suites

3.5 out of 5
1245 N. Brown St., La Plata, MO
3.74 km from city center
Stay at this 3.5-star family-friendly hotel in La Plata. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area

2.5 out of 5
1101 Country Club Dr, Kirksville, MO
20.27 km from city center
Book a stay at this golf hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Jacob's Vineyard & Winery and Thousand Hills ...
Hampton Inn Kirksville

Hampton Inn Kirksville

2.5 out of 5
2604 N. Baltimore Street, Kirksville, MO
25.57 km from city center
Book a stay at this business-friendly hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Super 8 by Wyndham Macon

Super 8 by Wyndham Macon

2 out of 5
203 E Briggs Dr, Macon, MO
28.68 km from city center
Stay at this motel in Macon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Baymont by Wyndham Kirksville University Area

Baymont by Wyndham Kirksville University Area

2.5 out of 5
2702 South Franklin, Kirksville, MO
20.27 km from city center
Book a stay at this business-friendly hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG

2.5 out of 5
2523 South Franklin St., Kirksville, MO
20.53 km from city center
Book a stay at this business-friendly hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
OYO Travelier Motel

OYO Travelier Motel

2.5 out of 5
201 E Briggs Dr, Macon, MO
28.68 km from city center
Stay at this hotel in Macon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Stephen's ...
Knights Inn Kirksville

Knights Inn Kirksville

1.5 out of 5
2521 South Franklin Street, Kirksville, MO
20.53 km from city center
Stay at this motel in Kirksville. Enjoy free parking, cable TV channels, and an in-room coffeemaker. Popular attractions Jacob's Vineyard & Winery and Thousand ...
Days Inn by Wyndham Kirksville

Days Inn by Wyndham Kirksville

2 out of 5
3805 S Baltimore St, Kirksville, MO
20.34 km from city center
Book a stay at this business-friendly hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr

2 out of 5
28933 Sunset Drive, Macon, MO
29.42 km from city center
Book a stay at this business-friendly motel in Macon. Enjoy free parking, a 24-hour front desk, and a business center. Popular attractions Long Branch State ...
Quality Inn Kirksville

Quality Inn Kirksville

2.5 out of 5
2209 N Baltimore St, Kirksville, MO
25.15 km from city center
Book a stay at this business-friendly hotel in Kirksville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
Budget Host Village Inn

Budget Host Village Inn

2 out of 5
1304 S Baltimore, Kirksville, MO
21.69 km from city center
Book a stay at this business-friendly motel in Kirksville. Enjoy free WiFi, free parking, and room service. Popular attractions Jacob's Vineyard & Winery and ...
Thousand Hills

Thousand Hills

2 out of 5
20431 Missouri 157, Kirksville, MO
24.8 km from city center
Stay at this hotel in Kirksville. Enjoy free parking, patios, and rainfall showerheads. Popular attractions Thousand Hills State Park and Jacob's Vineyard & ...
Don't see what you're looking for?
See all available properties in La Plata
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Sep 24 - Mon, Sep 29
PHL
Philadelphia Intl.
STL
Lambert-St. Louis Intl.
$174 Roundtrip, found 3 days ago
$174
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Sep 24 from Philadelphia Intl. to Lambert-St. Louis Intl., returning Mon, Sep 29, priced at $174 found 3 days ago
Frontier Airlines
Thu, Aug 28 - Sun, Sep 14
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$176 Roundtrip, found 6 days ago
$176
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Aug 28 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sun, Sep 14, priced at $176 found 6 days ago
Delta
Sat, Sep 13 - Tue, Sep 16
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$189 Roundtrip, found 5 days ago
$189
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Sep 13 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Tue, Sep 16, priced at $189 found 5 days ago
Spirit Airlines
Wed, Jul 9 - Thu, Jul 31
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$195 Roundtrip, found 6 days ago
$195
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Wed, Jul 9 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Jul 31, priced at $195 found 6 days ago
United
Fri, Aug 8 - Sun, Aug 10
DEN
Denver Intl.
MCI
Kansas City Intl.
$204 Roundtrip, found 5 days ago
$204
Roundtrip
found 5 days ago
Select United flight, departing Fri, Aug 8 from Denver Intl. to Kansas City Intl., returning Sun, Aug 10, priced at $204 found 5 days ago