Downtown Biloxi Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Downtown Biloxi Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express & Suites Ocean Springs by IHG

Holiday Inn Express & Suites Ocean Springs by IHG

2.5 out of 5
Save 100% on your flight
per person
Jul 24 - Jul 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to New Orleans (MSY)
Book a stay at this business-friendly hotel in Biloxi. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Hard Rock Casino Biloxi and Beau Rivage Casino are located nearby.

Virgin Hotels New Orleans

Virgin Hotels New Orleans

4.5 out of 5
New Orleans Central Business District
Save 100% on your flight
per person
Jul 22 - Jul 30
found 24 hours ago
Roundtrip flight included
Philadelphia (PHL) to New Orleans (MSY)
Stay at this 4.5-star luxury hotel in New Orleans. Enjoy free WiFi, 2 bars/lounges, and a rooftop terrace. Our guests praise the bar and the helpful staff in our reviews. Popular attractions Canal Street and National World War II Museum are located nearby.

Maison Dupuy Hotel

Maison Dupuy Hotel

3.5 out of 5
French Quarter
Save 100% on your flight
per person
Jul 22 - Jul 30
found 24 hours ago
Roundtrip flight included
Philadelphia (PHL) to New Orleans (MSY)
Book a stay at this historic hotel in New Orleans. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant in our reviews. Popular attractions Bourbon Street and Canal Street are located nearby.

Wyndham New Orleans - French Quarter

Wyndham New Orleans - French Quarter

4 out of 5
French Quarter
Save 100% on your flight
per person
Jul 22 - Jul 30
found 24 hours ago
Roundtrip flight included
Philadelphia (PHL) to New Orleans (MSY)
Book a stay at this business-friendly hotel in New Orleans. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Canal Street and Caesars New Orleans Casino are located nearby.

IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

4 out of 5
Save 100% on your flight
per person
Jul 24 - Jul 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to New Orleans (MSY)
Stay at this 4-star spa resort in Biloxi. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. Popular attractions Beau Rivage Casino and Hard Rock Casino Biloxi are located nearby.

Roami at The Luzianne

Roami at The Luzianne

4 out of 5
New Orleans Central Business District
Save 100% on your flight
per person
Jul 22 - Jul 30
found 24 hours ago
Roundtrip flight included
Philadelphia (PHL) to New Orleans (MSY)
Stay at this 4-star apartment in New Orleans. Enjoy free WiFi, Netflix, and in-room washers/dryers. Popular attractions Caesars New Orleans Casino and National World War II Museum are located nearby.

Don't see what you're looking for?
See all available trips from Columbus to Downtown Biloxi
View all trips

Top Hotel Deals

Hard Rock Hotel & Casino Biloxi

Hard Rock Hotel & Casino Biloxi

2 out of 5
777 Beach Blvd., Biloxi, MS
0.97 km from Downtown Biloxi
Stay at this hotel in Biloxi. Enjoy free WiFi, free parking, and 4 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. Popular attractions ...
Golden Nugget Biloxi

Golden Nugget Biloxi

4 out of 5
151 Beach Blvd, Biloxi, MS
1.45 km from Downtown Biloxi
Stay at this 4-star spa resort in Biloxi. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
Beau Rivage

Beau Rivage

4 out of 5
875 Beach Blvd, Biloxi, MS
1.31 km from Downtown Biloxi
Stay at this 4-star spa resort in Biloxi. Enjoy free parking, a full-service spa, and 10 restaurants. Our guests praise the pool and the helpful staff in our ...
The Hotel Legends

The Hotel Legends

3 out of 5
674 Beach Blvd, Biloxi, MS
0.67 km from Downtown Biloxi
Stay at this 3-star business-friendly hotel in Biloxi. Enjoy free WiFi, free parking, and a 24-hour health club. Our guests praise the pool and the restaurant ...
Best Western Oak Manor

Best Western Oak Manor

2.5 out of 5
886 Beach Boulevard, Biloxi, MS
1.35 km from Downtown Biloxi
Stay at this hotel in Biloxi. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Hilton Garden Inn Biloxi

Hilton Garden Inn Biloxi

3.5 out of 5
648 Beach Boulevard, Biloxi, MS
0.56 km from Downtown Biloxi
Stay at this 3.5-star business-friendly hotel in Biloxi. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Margaritaville Resort Biloxi

Margaritaville Resort Biloxi

3.5 out of 5
195 Beach Blvd, Biloxi, MS
1.55 km from Downtown Biloxi
Stay at this 3.5-star beach hotel in Biloxi. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the pool and the helpful staff in our reviews. ...
IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

4 out of 5
850 Bayview Ave, Biloxi, MS
2.28 km from Downtown Biloxi
Stay at this 4-star spa resort in Biloxi. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. Popular ...
Palace Casino Resort

Palace Casino Resort

4 out of 5
158 Howard Ave, Biloxi, MS
1.64 km from Downtown Biloxi
Stay at this 4-star spa hotel in Biloxi. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
Harrah's Gulf Coast

Harrah's Gulf Coast

4 out of 5
280 Beach Boulevard, Biloxi, MS
1.16 km from Downtown Biloxi
Book a stay at this spa resort in Biloxi. Enjoy free parking, a full-service spa, and 8 restaurants. Our guests praise the helpful staff and the clean rooms ...
Hyatt Place Biloxi

Hyatt Place Biloxi

3 out of 5
1150 Beach Blvd, Biloxi, MS
2.7 km from Downtown Biloxi
Stay at this 3-star beach hotel in Biloxi. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Best Western Seaway Inn

Best Western Seaway Inn

2.5 out of 5
9475 US 49, Gulfport, MS
20.86 km from Downtown Biloxi
Book a stay at this business-friendly hotel in Gulfport. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Scarlet Pearl Casino Resort

Scarlet Pearl Casino Resort

4 out of 5
9380 Central Ave, D'Iberville, MS
3.63 km from Downtown Biloxi
Stay at this 4-star business-friendly hotel in D'Iberville. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff and the clean ...
Comfort Inn & Suites Crystal Inn Sportsplex

Comfort Inn & Suites Crystal Inn Sportsplex

2.5 out of 5
9379 Canal Rd, Gulfport, MS
25.23 km from Downtown Biloxi
Book a stay at this business-friendly hotel in Gulfport. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Country Inn & Suites by Radisson, Biloxi-Ocean Springs, MS

Country Inn & Suites by Radisson, Biloxi-Ocean Springs, MS

2.5 out of 5
13900 Wilfred Seymour Rd, Ocean Springs, MS
7.71 km from Downtown Biloxi
Book a stay at this business-friendly hotel in Ocean Springs. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Don't see what you're looking for?
See all available properties in Downtown Biloxi
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Thu, Jun 19 - Sun, Jun 22
ATL
Hartsfield-Jackson Atlanta Intl.
MSY
Louis Armstrong New Orleans Intl.
$86 Roundtrip, found 3 days ago
$86
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Thu, Jun 19 from Hartsfield-Jackson Atlanta Intl. to Louis Armstrong New Orleans Intl., returning Sun, Jun 22, priced at $86 found 3 days ago
Spirit Airlines
Thu, Jul 10 - Sun, Jul 13
DFW
Dallas-Fort Worth Intl.
MSY
Louis Armstrong New Orleans Intl.
$121 Roundtrip, found 15 hours ago
$121
Roundtrip
found 15 hours ago
Select Spirit Airlines flight, departing Thu, Jul 10 from Dallas-Fort Worth Intl. to Louis Armstrong New Orleans Intl., returning Sun, Jul 13, priced at $121 found 15 hours ago
Spirit Airlines
Tue, Jun 17 - Tue, Jun 24
LAX
Los Angeles Intl.
MSY
Louis Armstrong New Orleans Intl.
$122 Roundtrip, found 3 days ago
$122
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, Jun 17 from Los Angeles Intl. to Louis Armstrong New Orleans Intl., returning Tue, Jun 24, priced at $122 found 3 days ago
Frontier Airlines
Thu, Oct 9 - Thu, Oct 16
PHL
Philadelphia Intl.
MSY
Louis Armstrong New Orleans Intl.
$134 Roundtrip, found 4 days ago
$134
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Oct 9 from Philadelphia Intl. to Louis Armstrong New Orleans Intl., returning Thu, Oct 16, priced at $134 found 4 days ago