Downtown Biloxi Vacation Packages for 2025

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Downtown Biloxi Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Wyndham Garden Hotel Baronne Plaza

Wyndham Garden Hotel Baronne Plaza

3 out of 5
New Orleans Central Business District
per person
Sep 15 - Sep 19
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to New Orleans (MSY)
Stay at this 3-star historic hotel in New Orleans. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Canal Street and Caesars New Orleans Casino are located nearby.

Maison Dupuy Hotel

Maison Dupuy Hotel

3.5 out of 5
French Quarter
Save 100% on your flight
per person
Sep 15 - Sep 19
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to New Orleans (MSY)
Stay at this 3.5-star historic hotel in New Orleans. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant in our reviews. Popular attractions Bourbon Street and Canal Street are located nearby.

NOPSI Hotel, New Orleans

NOPSI Hotel, New Orleans

4.5 out of 5
New Orleans Central Business District
Save 100% on your flight
per person
Sep 15 - Sep 19
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to New Orleans (MSY)
Stay at this 4.5-star luxury hotel in New Orleans. Enjoy 3 bars/lounges, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our reviews. Popular attractions Canal Street and Caesars Superdome are located nearby.

Inn on St. Peter

Inn on St. Peter

3 out of 5
French Quarter
per person
Sep 15 - Sep 19
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to New Orleans (MSY)
Stay at this 3-star historic hotel in New Orleans. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Bourbon Street and Canal Street are located nearby.

Inn on St Ann

Inn on St Ann

3 out of 5
French Quarter
per person
Sep 15 - Sep 19
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to New Orleans (MSY)
Stay at this 3-star historic hotel in New Orleans. Enjoy free WiFi, a 24-hour front desk, and concierge services. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Bourbon Street and Canal Street are located nearby.

The Barnett, part of JdV by Hyatt

The Barnett, part of JdV by Hyatt

4 out of 5
New Orleans Central Business District
per person
Sep 15 - Sep 19
found 16 hours ago
Roundtrip flight included
Detroit (DTW) to New Orleans (MSY)
Stay at this 4-star business-friendly hotel in New Orleans. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the bar and the helpful staff in our reviews. Popular attractions Canal Street and National World War II Museum are located nearby.

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Top Hotel Deals

Hard Rock Hotel & Casino Biloxi

Hard Rock Hotel & Casino Biloxi

4 out of 5
777 Beach Blvd., Biloxi, MS
0.97 km from Downtown Biloxi
Stay at this 4-star hotel in Biloxi. Enjoy free WiFi, free parking, and 4 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. Popular ...
Golden Nugget Biloxi

Golden Nugget Biloxi

4 out of 5
151 Beach Blvd, Biloxi, MS
1.45 km from Downtown Biloxi
Stay at this 4-star spa resort in Biloxi. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff in our ...
The Hotel Legends

The Hotel Legends

3 out of 5
674 Beach Blvd, Biloxi, MS
0.67 km from Downtown Biloxi
Stay at this 3-star business-friendly hotel in Biloxi. Enjoy free WiFi, free parking, and a 24-hour health club. Our guests praise the pool and the restaurant ...
Beau Rivage

Beau Rivage

4 out of 5
875 Beach Blvd, Biloxi, MS
1.31 km from Downtown Biloxi
Stay at this 4-star spa resort in Biloxi. Enjoy free parking, a full-service spa, and 10 restaurants. Our guests praise the pool and the helpful staff in our ...
Best Western Oak Manor

Best Western Oak Manor

2.5 out of 5
886 Beach Boulevard, Biloxi, MS
1.35 km from Downtown Biloxi
Stay at this hotel in Biloxi. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Hilton Garden Inn Biloxi

Hilton Garden Inn Biloxi

3.5 out of 5
648 Beach Boulevard, Biloxi, MS
0.56 km from Downtown Biloxi
Stay at this 3.5-star business-friendly hotel in Biloxi. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Margaritaville Resort Biloxi

Margaritaville Resort Biloxi

3.5 out of 5
195 Beach Blvd, Biloxi, MS
1.55 km from Downtown Biloxi
Stay at this 3.5-star beach hotel in Biloxi. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the pool and the helpful staff in our reviews. ...
IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi

4 out of 5
850 Bayview Ave, Biloxi, MS
2.28 km from Downtown Biloxi
Stay at this 4-star spa resort in Biloxi. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. Popular ...
Palace Casino Resort

Palace Casino Resort

4 out of 5
158 Howard Ave, Biloxi, MS
1.64 km from Downtown Biloxi
Stay at this 4-star spa hotel in Biloxi. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
Hyatt Place Biloxi

Hyatt Place Biloxi

3 out of 5
1150 Beach Blvd, Biloxi, MS
2.7 km from Downtown Biloxi
Stay at this 3-star beach hotel in Biloxi. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Centennial Plaza Resort Gulfport

Centennial Plaza Resort Gulfport

2.5 out of 5
200 E. Beach Blvd, Gulfport, MS
16.83 km from Downtown Biloxi
Book a stay at this family-friendly hotel in Gulfport. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the helpful staff in ...
Scarlet Pearl Casino Resort

Scarlet Pearl Casino Resort

4 out of 5
9380 Central Ave, D'Iberville, MS
3.63 km from Downtown Biloxi
Stay at this 4-star business-friendly hotel in D'Iberville. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff and the clean ...
Best Western Seaway Inn

Best Western Seaway Inn

2.5 out of 5
9475 US 49, Gulfport, MS
20.86 km from Downtown Biloxi
Book a stay at this business-friendly hotel in Gulfport. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Comfort Inn & Suites Crystal Inn Sportsplex

Comfort Inn & Suites Crystal Inn Sportsplex

2.5 out of 5
9379 Canal Rd, Gulfport, MS
25.23 km from Downtown Biloxi
Book a stay at this business-friendly hotel in Gulfport. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Super 8 by Wyndham Ocean Springs Biloxi

Super 8 by Wyndham Ocean Springs Biloxi

2 out of 5
13838 Wilfred Seymour Rd, Ocean Springs, MS
7.68 km from Downtown Biloxi
Book a stay at this business-friendly motel in Ocean Springs. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Sat, Nov 1 - Fri, Nov 7
ATL
Hartsfield-Jackson Atlanta Intl.
MSY
Louis Armstrong New Orleans Intl.
$58 Roundtrip, found 6 days ago
$58
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Sat, Nov 1 from Hartsfield-Jackson Atlanta Intl. to Louis Armstrong New Orleans Intl., returning Fri, Nov 7, priced at $58 found 6 days ago
Delta
Mon, Oct 20 - Wed, Oct 29
LGA
LaGuardia
MSY
Louis Armstrong New Orleans Intl.
$139 Roundtrip, found 6 days ago
$139
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Oct 20 from LaGuardia to Louis Armstrong New Orleans Intl., returning Wed, Oct 29, priced at $139 found 6 days ago
United
Mon, Sep 8 - Wed, Sep 17
EWR
Newark Liberty Intl. Airport
MSY
Louis Armstrong New Orleans Intl.
$139 Roundtrip, found 5 days ago
$139
Roundtrip
found 5 days ago
Select United flight, departing Mon, Sep 8 from Newark Liberty Intl. Airport to Louis Armstrong New Orleans Intl., returning Wed, Sep 17, priced at $139 found 5 days ago
JetBlue Airways
Mon, Oct 13 - Thu, Oct 16
JFK
John F. Kennedy Intl.
MSY
Louis Armstrong New Orleans Intl.
$157 Roundtrip, found 1 day ago
$157
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Mon, Oct 13 from John F. Kennedy Intl. to Louis Armstrong New Orleans Intl., returning Thu, Oct 16, priced at $157 found 1 day ago
Alaska Airlines
Wed, Sep 17 - Mon, Sep 22
LAX
Los Angeles Intl.
MSY
Louis Armstrong New Orleans Intl.
$212 Roundtrip, found 1 day ago
$212
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Wed, Sep 17 from Los Angeles Intl. to Louis Armstrong New Orleans Intl., returning Mon, Sep 22, priced at $212 found 1 day ago