A cityscape at dusk with a prominent government building featuring a large dome and classical architecture.

Resorts & Hotels with Spas in Mississippi

Top Cities in Mississippi

A beach with wooden chairs and colorful umbrellas, a pier extending into the water, and a lifeguard tower in the background.
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Biloxi

Biloxi

Check availability on Mississippi Resorts & Hotels with Spas

This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Our top choices for Mississippi hotels with a spa

A reception desk with a dark, textured surface and decorative leaf patterns. It features multiple shelves with various items and a central vase with flowers.

1. The Westin Jackson

The Westin Jackson
4.0 star property
Downtown Jackson
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Immerse in a luxurious wellness retreat with 7 serene treatment rooms at Soul Spa, complemented by an indoor pool and exceptional dining.
The Westin Jackson
A well-furnished living room with a sofa, armchairs, a coffee table, and a large abstract painting on the wall.

2. Beau Rivage

Beau Rivage
4.0 star property
Downtown Biloxi
9.4 out of 10, Exceptional, (1,442 reviews)
  • cleanliness
    Revitalize at this waterfront resort with 14 treatment rooms and couples massage suites where deep soaking tubs complement spa journeys.
Beau Rivage
A modern hotel lobby with a reception desk, seating area, and unique lighting fixtures.

3. Tru By Hilton Tupelo

Tru By Hilton Tupelo
2.5 star property
Tupelo
9.2 out of 10, Wonderful, (796 reviews)
Tru By Hilton Tupelo
Exterior

4. Hilton Garden Inn Memphis/Southaven, MS

Hilton Garden Inn Memphis/Southaven, MS
3.0 star property
Southaven
8.6 out of 10, Excellent, (1,003 reviews)
Hilton Garden Inn Memphis/Southaven, MS
A spacious lobby with a reception desk, seating area, and large windows.

5. Hampton Inn Jackson/Flowood (Airport Area) MS

Hampton Inn Jackson/Flowood (Airport Area) MS
2.5 star property
Flowood
9.0 out of 10, Wonderful, (1,000 reviews)
Hampton Inn Jackson/Flowood (Airport Area) MS
A hotel pool with sunbathing chairs, a water feature, and a view of the sunset.

6. Silver Slipper Casino & Hotel - Adults Only

Silver Slipper Casino & Hotel - Adults Only
3.5 star property
Bay St Louis
8.6 out of 10, Excellent, (1,001 reviews)
Silver Slipper Casino & Hotel - Adults Only
An outdoor patio with seating, a fire pit, and string lights.

7. Home2 Suites by Hilton Jackson/Pearl, MS

Home2 Suites by Hilton Jackson/Pearl, MS
3.0 star property
Pearl
8.8 out of 10, Excellent, (1,002 reviews)
Home2 Suites by Hilton Jackson/Pearl, MS
A hotel named 'HOTEL DESOTO' with a modern facade, numbered address 8877, and a symmetrical window design.

8. Hotel DeSoto

Hotel DeSoto
2.5 star property
Olive Branch
8.8 out of 10, Excellent, (1,003 reviews)
Hotel DeSoto
A modern hotel with a covered entrance, multiple floors, and a well-lit facade.

9. La Quinta Inn & Suites by Wyndham Oxford

La Quinta Inn & Suites by Wyndham Oxford
3.0 star property
Oxford
9.2 out of 10, Wonderful, (1,003 reviews)
La Quinta Inn & Suites by Wyndham Oxford
A reception area with a wooden partition, two grey upholstered chairs, a desk with a lamp, and a mirror above the counter.

10. Holiday Inn Express and Suites Winona North by IHG

Holiday Inn Express and Suites Winona North by IHG
2.5 star property
Winona
8.2 out of 10, Very good, (755 reviews)
Holiday Inn Express and Suites Winona North by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi Hotel Reviews

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