Luxury Hotels in Mississippi

Start date: Check-in selected.
End date: Check-out

Top Cities in Mississippi

Biloxi Beach showing a sandy beach and general coastal views
HotelsHotels

Biloxi

Biloxi

Check availability on Mississippi Luxury Hotels

Tonight
Sep 1 - Sep 2
Tomorrow
Sep 2 - Sep 3
This weekend
Sep 5 - Sep 7
Next weekend
Sep 12 - Sep 14

Pick from 121 Mississippi Luxury Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Mississippi luxury hotels

Beau Rivage
Outdoor pool, open 8:00 AM to 8:00 PM, sun loungers

Beau Rivage

4.0 star property
9.2 out of 10, Wonderful, (1405)
"Comfortable and spacious guest rooms with friendly and helpful staff"
Beau Rivage
Margaritaville Resort Biloxi
Interior detail

Margaritaville Resort Biloxi

3.5 star property
8.6 out of 10, Excellent, (5293)
"Everything was Nice we really enjoyed our stay."
Margaritaville Resort Biloxi
White House Hotel
Exterior

White House Hotel

3.0 star property
8.8 out of 10, Excellent, (1007)
"Great stay"
White House Hotel
The Guest House Historic Mansion
Room, 1 Queen Bed (John R. Lynch) | Pillowtop beds, desk, blackout drapes, iron/ironing board

The Guest House Historic Mansion

3.5 star property
9.2 out of 10, Wonderful, (793)
"Awesome hotel and great staff. I look forward to returning to this hotel"
The Guest House Historic Mansion
IP Casino Resort Spa - Biloxi
Couples treatment rooms, sauna, hot tub, steam room, body treatments

IP Casino Resort Spa - Biloxi

4.0 star property
8.6 out of 10, Excellent, (4976)
"Great property we had a wonderful time. "
IP Casino Resort Spa - Biloxi
Duff Green Mansion
Courtyard view

Duff Green Mansion

4.0 star property
9.4 out of 10, Exceptional, (919)
"It was quiet and relaxing. The staff was very accommodating and friendly. Loved the house "
Duff Green Mansion
Gold Strike Casino Resort
Reception

Gold Strike Casino Resort

3.5 star property
8.2 out of 10, Very Good, (1014)
"The hotel was clean rooms nice. "
Gold Strike Casino Resort
Golden Nugget Biloxi
2 outdoor pools, cabanas (surcharge), pool umbrellas

Golden Nugget Biloxi

4.0 star property
8.0 out of 10, Very Good, (2592)
"Rooms are comfortable, staff are attentive & great location!"
Golden Nugget Biloxi
Best Western Airport Inn
Free full breakfast

Best Western Airport Inn

2.5 star property
7.8 out of 10, Good, (1004)
"Great service every time I stay!"
Best Western Airport Inn
Quality Inn
Free daily continental breakfast

Quality Inn

2.5 star property
7.8 out of 10, Good, (712)
"Nice breakfast Nice staff."
Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mississippi Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia