Central Vacations

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Photo by Ryan Watts
Choose two or more items and save on your trip:

Top Hotel Deals

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St, Clemson, SC
6.83 km from city center
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd, Anderson, SC
18.41 km from city center
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
8.15 km from city center
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd, Clemson, SC
5.67 km from city center
Book a stay at this business-friendly hotel in Clemson. Enjoy free parking, an outdoor pool, and a 24-hour fitness center. Our guests praise the helpful staff ...
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd, Clemson, SC
5.64 km from city center
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Horizon Inn & Suites

Horizon Inn & Suites

2 out of 5
3025 N Main Street, Anderson, SC
23.31 km from city center
Stay at this hotel in Anderson. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Anderson Mall and North Anderson Park are located ...
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
4.18 km from city center
Stay at this 3-star cottage in Clemson. Enjoy free parking and air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy ...
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd, Clemson, SC
5.66 km from city center
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2 out of 5
102 Electric City Blvd, Anderson, SC
17.28 km from city center
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive, Clemson, SC
8.7 km from city center
Stay at this 3-star golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street, Seneca, SC
14.78 km from city center
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd, Seneca, SC
16.41 km from city center
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Best Western Plus Greenville South

Best Western Plus Greenville South

2.5 out of 5
70 Kalyns Way, Piedmont, SC
29.42 km from city center
Book a stay at this business-friendly hotel in Piedmont. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Comfort Suites Greenville South

Comfort Suites Greenville South

2.5 out of 5
10 Kalyns Way, Piedmont, SC
29.3 km from city center
Book a stay at this business-friendly hotel in Piedmont. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG

2.5 out of 5
1381 Tiger Blvd, Clemson, SC
5.25 km from city center
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Don't see what you're looking for?
See all available properties in Central
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Oct 23 - Mon, Oct 27
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$197 Roundtrip, found 6 days ago
$197
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Oct 23 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Oct 27, priced at $197 found 6 days ago
American Airlines
Thu, Oct 23 - Mon, Oct 27
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 22 hours ago
$209
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Thu, Oct 23 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Oct 27, priced at $209 found 22 hours ago
United
Tue, Jul 29 - Thu, Aug 7
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 3 days ago
$209
Roundtrip
found 3 days ago
Select United flight, departing Tue, Jul 29 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Thu, Aug 7, priced at $209 found 3 days ago
United
Thu, Jul 31 - Mon, Aug 4
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$219 Roundtrip, found 2 days ago
$219
Roundtrip
found 2 days ago
Select United flight, departing Thu, Jul 31 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Mon, Aug 4, priced at $219 found 2 days ago