Central Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Central Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
$555
per person
Nov 11 - Nov 16
found 22 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room service in our reviews. Popular attractions Bon Secours Wellness Arena and Falls Park on the Reedy are located nearby.
Great customer service. Definitely cleanliness too of the line as well.
Reviewed on Aug 31, 2026
Hotel Hartness
$878
per person
Nov 11 - Nov 16
found 22 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Greenville (GSP)
Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Topgolf Greenville and LeMans Karting are located nearby.
Holiday Inn Greenville - Woodruff Road by IHG
$602
per person
Nov 11 - Nov 16
found 22 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Haywood Mall and Bon Secours Wellness Arena are located nearby.
Awesome breakfast
Reviewed on Aug 29, 2026
Hilton Greenville
$758
per person
Nov 11 - Nov 16
found 22 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Greenville (GSP)
Book a stay at this family-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Bon Secours Wellness Arena and Falls Park on the Reedy are located nearby.
AC Hotel By Marriott Greenville
Greenville Downtown
$1,343
per person
Nov 11 - Nov 16
found 22 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Falls Park on the Reedy and Bon Secours Wellness Arena are located nearby.
Everything was GREAT EXCEPT....for the parking. The gate did not provide us a ticket but the front desk assisted us in exiting out of the garage.🙂
Reviewed on Aug 31, 2026
Comfort Inn Greenville - Haywood Mall
$598
per person
Nov 11 - Nov 16
found 22 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Greenville (GSP)
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Haywood Mall and Bon Secours Wellness Arena are located nearby.
Top Hotel Deals
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Inn @ Clemson
1303 Tiger Blvd Clemson SC
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Courtyard Marriott Clemson
201 Canoy Ln Clemson SC
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Clemson Area African American ...
Clemson University's James F. Martin Inn
240 Madren Center Drive Clemson SC
Book a stay at this golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
107 Interstate Blvd Anderson SC
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
The Abernathy of Clemson
157 Old Greenville Hwy Clemson SC
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Fairfield Inn & Suites Seneca Clemson Univ Area
800 BYPASS 123 Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
The Inn at Patrick Square
115 Market Street Clemson SC
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreation Area and Cross Creek Plantation Golf ...
Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Quality Inn Clemson near University
3430 Clemson Blvd Anderson SC
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Fri, Oct 9 - Sun, Oct 11
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$319
Roundtrip
found 4 days ago
Tue, Oct 6 - Wed, Oct 14
MDW
Midway Intl.
GSP
Greenville-Spartanburg Intl.
$319
Roundtrip
found 2 hours ago
Tue, Oct 6 - Wed, Oct 14
MDW
Midway Intl.
GSP
Greenville-Spartanburg Intl.
$319
Roundtrip
found 2 hours ago
Wed, Sep 16 - Wed, Sep 23
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$339
Roundtrip
found 4 days ago
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