5 Star Rome Historic Centre Hotels In 2026

Choose two or more items and save on your trip:

Featured Rome Historic Centre 5 Star Hotels

InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG

5 out of 5
Via V. Veneto 62 Rome RM
InterContinental Rome Ambasciatori Palace by IHG
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

5 out of 5
Piazza Dei Cinquecento, 90 Rome RM
NH Collection Roma Palazzo Cinquecento
W Rome

W Rome

5 out of 5
26/36 Via Liguria Rome RM
W Rome
Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World

5 out of 5
Via Di Porta Pinciana 14 Rome RM
Hotel Splendide Royal - The Leading Hotels of the World
Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica

5 out of 5
VIA DELLE BOTTEGHE OSCURE 46 Rome RM
Radisson Collection Hotel, Roma Antica
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

5 out of 5
Piazza Della Repubblica, 47 Rome RM
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
The Rome EDITION

The Rome EDITION

5 out of 5
SALITA DI SAN NICOLA DA TOLENTINO 14 Rome RM
The Rome EDITION
Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux

5 out of 5
Largo Febo Rome RM
Hotel Raphaël – Relais & Châteaux
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World

5 out of 5
Via del Gianicolo 3 Rome RM
Villa Agrippina Gran Meliá - The Leading Hotels of the World
See all 7,828 properties in Rome Historic Centre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.