2025 5 Star Hotels in Mission Valley

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Featured Mission Valley 5 Star Hotels

Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street San Diego CA
Fully refundableReserve now, pay when you stay
Pendry San Diego
The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego

5 out of 5
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
The US Grant, a Luxury Collection Hotel, San Diego
Fairmont Grand Del Mar

Fairmont Grand Del Mar

5 out of 5
5300 Grand Del Mar Court San Diego CA
Fully refundableReserve now, pay when you stay
Fairmont Grand Del Mar
L'Auberge Del Mar

L'Auberge Del Mar

5 out of 5
1540 Camino Del Mar Del Mar CA
Fully refundableReserve now, pay when you stay
L'Auberge Del Mar
The Lodge at Torrey Pines

The Lodge at Torrey Pines

5 out of 5
11480 N Torrey Pines Rd La Jolla CA
Fully refundableReserve now, pay when you stay
The Lodge at Torrey Pines
Shore House at The Del, LXR Hotels & Resorts

Shore House at The Del, LXR Hotels & Resorts

5 out of 5
1500 Orange Avenue Coronado CA
Shore House at The Del, LXR Hotels & Resorts
Beach Village at The Del, LXR Hotels & Resorts

Beach Village at The Del, LXR Hotels & Resorts

5 out of 5
1500 Orange Avenue Coronado CA
Beach Village at The Del, LXR Hotels & Resorts
The Bower Coronado

The Bower Coronado

5 out of 5
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
The Bower Coronado
Inn At Rancho Santa Fe

Inn At Rancho Santa Fe

5 out of 5
5951 Linea Del Cielo Rancho Santa Fe CA
Fully refundableReserve now, pay when you stay
Inn At Rancho Santa Fe
See all 8,816 properties in Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.