2025 5 Star Hotels in Guadalupe

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Featured Guadalupe 5 Star Hotels

Arizona Biltmore, LXR Hotels & Resorts

Arizona Biltmore, LXR Hotels & Resorts

5 out of 5
2400 E Missouri Avenue Phoenix AZ
Fully refundableReserve now, pay when you stay
Arizona Biltmore, LXR Hotels & Resorts
Royal Palms Resort and Spa, part of Hyatt

Royal Palms Resort and Spa, part of Hyatt

5 out of 5
5200 E Camelback Road Phoenix AZ
Fully refundableReserve now, pay when you stay
Royal Palms Resort and Spa, part of Hyatt
Andaz Scottsdale Resort & Bungalows

Andaz Scottsdale Resort & Bungalows

5 out of 5
6114 N Scottsdale Road Paradise Valley AZ
Fully refundableReserve now, pay when you stay
Andaz Scottsdale Resort & Bungalows
Sanctuary Camelback Mountain Resort and Spa

Sanctuary Camelback Mountain Resort and Spa

5 out of 5
5700 E McDonald Drive Paradise Valley AZ
Fully refundableReserve now, pay when you stay
Sanctuary Camelback Mountain Resort and Spa
The Phoenician, a Luxury Collection Resort, Scottsdale

The Phoenician, a Luxury Collection Resort, Scottsdale

5 out of 5
6000 E Camelback Rd Paradise Valley AZ
Fully refundableReserve now, pay when you stay
The Phoenician, a Luxury Collection Resort, Scottsdale
The Canyon Suites at The Phoenician, Luxury Collection

The Canyon Suites at The Phoenician, Luxury Collection

5 out of 5
6000 E Camelback Rd Scottsdale AZ
The Canyon Suites at The Phoenician, Luxury Collection
Casa De Encanto

Casa De Encanto

5 out of 5
9748 E Becker Ln Scottsdale AZ
Casa De Encanto
Hidden Paradise

Hidden Paradise

5 out of 5
12649 E Silverspur St Scottsdale AZ
Hidden Paradise
Golfers Paradise W/pickleball & Heated Pool & Spa!

Golfers Paradise W/pickleball & Heated Pool & Spa!

5 out of 5
6124 E Delcoa Ave Scottsdale AZ
Golfers Paradise W/pickleball & Heated Pool & Spa!
See all 12,383 properties in Guadalupe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.