2025 4 Star Hotels in Texas Medical Center

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Featured Texas Medical Center 4 Star Hotels

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd, Houston, TX
Fully refundableReserve now, pay when you stay
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street, Houston, TX
Club Quarters Hotel Downtown, Houston
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
Hotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
Hilton Houston Plaza/Medical Center
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Houston
Fully refundableReserve now, pay when you stay
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel

4 out of 5
1100 Texas St, Houston, TX
Fully refundableReserve now, pay when you stay
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Omni Houston Hotel

Omni Houston Hotel

4 out of 5
4 Riverway, Houston, TX
Fully refundableReserve now, pay when you stay
Omni Houston Hotel
C. Baldwin, Curio Collection by Hilton

C. Baldwin, Curio Collection by Hilton

4 out of 5
400 Dallas St, Houston, TX
C. Baldwin, Curio Collection by Hilton
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave, Houston, TX
Blossom Hotel Houston, Curio Collection by Hilton
See all 6,625 properties in Texas Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.