2026 4 Star Hotels in Midtown

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Featured Midtown 4 Star Hotels

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
Hotel Zaza Houston Museum District
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
The Royal Sonesta Houston Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Club Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
Hilton Houston Plaza/Medical Center
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
Blossom Hotel Houston, Curio Collection by Hilton
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
The Whitehall Houston
Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria

4 out of 5
2626 Sage Road Houston TX
Fully refundableReserve now, pay when you stay
Hyatt Regency Houston/Galleria
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Houston TX
Fully refundableReserve now, pay when you stay
DoubleTree by Hilton Hotel Houston - Greenway Plaza
See all 6,637 properties in Midtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.