2026 4 Star Hotels in Matecumbe

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Featured Matecumbe 4 Star Hotels

Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
Amara Cay Resort
Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
Islander Resort
La Siesta Resort & Villas

La Siesta Resort & Villas

4 out of 5
80241 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
La Siesta Resort & Villas
The Islands of Islamorada

The Islands of Islamorada

4 out of 5
82779 Old Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
The Islands of Islamorada
Turtle Nest Estate by Florida Keys Luxury Rentals

Turtle Nest Estate by Florida Keys Luxury Rentals

4 out of 5
75971 Overseas Highway Islamorada FL
Turtle Nest Estate by Florida Keys Luxury Rentals
Serenity by Florida Keys Luxury Rentals

Serenity by Florida Keys Luxury Rentals

4 out of 5
75631 Overseas Highway Islamorada FL
Serenity by Florida Keys Luxury Rentals
See all 569 properties in Matecumbe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.