2025 4 Star Hotels in East Palo Alto

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Featured East Palo Alto 4 Star Hotels

Sonesta Silicon Valley

Sonesta Silicon Valley

4 out of 5
1820 Barber Ln Milpitas CA
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Sonesta Silicon Valley
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
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Grand Hyatt at SFO
The Westin San Jose

The Westin San Jose

4 out of 5
302 South Market Street San Jose CA
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The Westin San Jose
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

4 out of 5
600 Airport Boulevard Burlingame CA
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Hilton San Francisco Airport Bayfront
The Domain Hotel

The Domain Hotel

4 out of 5
1085 E El Camino Real Sunnyvale CA
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The Domain Hotel
Hotel De Anza

Hotel De Anza

4 out of 5
233 W Santa Clara St San Jose CA
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Hotel De Anza
The Westin San Francisco Airport

The Westin San Francisco Airport

4 out of 5
1 Old Bayshore Hwy Millbrae CA
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The Westin San Francisco Airport
Hyatt Regency Santa Clara

Hyatt Regency Santa Clara

4 out of 5
5101 Great America Pkwy Santa Clara CA
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Hyatt Regency Santa Clara
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

4 out of 5
1333 Bayshore Hwy Burlingame CA
Fully refundableReserve now, pay when you stay
Hyatt Regency San Francisco Airport
See all 3,256 properties in East Palo Alto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.