Flights from Des Moines to Buffalo

Cheapest flights from Des Moines

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$367 Roundtrip, found 1 day ago

$367

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $367 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$372 Roundtrip, found 1 day ago

$372

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $372 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$394 Roundtrip, found 1 day ago

$394

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $394 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$408 Roundtrip, found 1 day ago

$408

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $408 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$413 Roundtrip, found 1 day ago

$413

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $413 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$429 Roundtrip, found 1 day ago

$429

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $429 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$435 Roundtrip, found 1 day ago

$435

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $435 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$437 Roundtrip, found 1 day ago

$437

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $437 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$442 Roundtrip, found 1 day ago

$442

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $442 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$449 Roundtrip, found 1 day ago

$449

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $449 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$470 Roundtrip, found 1 day ago

$470

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $470 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$478 Roundtrip, found 1 day ago

$478

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $478 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$479 Roundtrip, found 1 day ago

$479

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $479 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$482 Roundtrip, found 1 day ago

$482

Roundtrip

found 1 day ago

Select Delta flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $482 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$483 Roundtrip, found 1 day ago

$483

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $483 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$488 Roundtrip, found 1 day ago

$488

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $488 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$496 Roundtrip, found 1 day ago

$496

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $496 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$501 Roundtrip, found 1 day ago

$501

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $501 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$519 Roundtrip, found 1 day ago

$519

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $519 found 1 day ago

Sun, Aug 3 - Wed, Aug 6

DSM

Des Moines Intl.

BUF

Buffalo Niagara Intl.

$564 Roundtrip, found 1 day ago

$564

Roundtrip

found 1 day ago

Select United flight, departing Sun, Aug 3 from Des Moines Intl. to Buffalo Niagara Intl., returning Wed, Aug 6, priced at $564 found 1 day ago