Flights from Des Moines to Chicago

Cheapest flights from Des Moines

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$210 Roundtrip, found 1 day ago

$210

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $210 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$219 Roundtrip, found 1 day ago

$219

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $219 found 1 day ago

Sun, Jul 27 - Tue, Aug 5

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$229 Roundtrip, found 1 day ago

$229

Roundtrip

found 1 day ago

Select Delta flight, departing Sun, Jul 27 from Des Moines Intl. to O'Hare Intl., returning Tue, Aug 5, priced at $229 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$240 Roundtrip, found 1 day ago

$240

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $240 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$242 Roundtrip, found 1 day ago

$242

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $242 found 1 day ago

Wed, Jul 23 - Mon, Aug 4

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$249 Roundtrip, found 1 day ago

$249

Roundtrip

found 1 day ago

Select American Airlines flight, departing Wed, Jul 23 from Des Moines Intl. to O'Hare Intl., returning Mon, Aug 4, priced at $249 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$259 Roundtrip, found 1 day ago

$259

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $259 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$270 Roundtrip, found 1 day ago

$270

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $270 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$272 Roundtrip, found 1 day ago

$272

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $272 found 1 day ago

Wed, Jul 23 - Fri, Aug 1

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$279 Roundtrip, found 1 day ago

$279

Roundtrip

found 1 day ago

Select United flight, departing Wed, Jul 23 from Des Moines Intl. to O'Hare Intl., returning Fri, Aug 1, priced at $279 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$289 Roundtrip, found 1 day ago

$289

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $289 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$300 Roundtrip, found 1 day ago

$300

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $300 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$302 Roundtrip, found 1 day ago

$302

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $302 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$308 Roundtrip, found 1 day ago

$308

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $308 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$309 Roundtrip, found 1 day ago

$309

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $309 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$318 Roundtrip, found 1 day ago

$318

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $318 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$319 Roundtrip, found 1 day ago

$319

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $319 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$332 Roundtrip, found 1 day ago

$332

Roundtrip

found 1 day ago

Select United flight, departing Sat, Jul 26 from Des Moines Intl. to O'Hare Intl., returning Mon, Jul 28, priced at $332 found 1 day ago

Sun, Jul 27 - Sat, Aug 2

DSM

Des Moines Intl.

ORD

O'Hare Intl.

$333 Roundtrip, found 1 day ago

$333

Roundtrip

found 1 day ago

Select Delta flight, departing Sun, Jul 27 from Des Moines Intl. to O'Hare Intl., returning Sat, Aug 2, priced at $333 found 1 day ago

Sat, Jul 26 - Mon, Jul 28

DSM

Des Moines Intl.

MDW

Midway Intl.

$420 Roundtrip, found 1 day ago

$420

Roundtrip

found 1 day ago

Select Delta flight, departing Sat, Jul 26 from Des Moines Intl. to Midway Intl., returning Mon, Jul 28, priced at $420 found 1 day ago