Flights from Detroit to San Francisco

Cheapest flights from Detroit

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jun 20 - Tue, Jun 24

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$229 Roundtrip, found 3 hours ago

$229

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Fri, Jun 20 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Tue, Jun 24, priced at $229 found 3 hours ago

Fri, Jun 20 - Wed, Jun 25

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$247 Roundtrip, found 3 hours ago

$247

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Fri, Jun 20 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Wed, Jun 25, priced at $247 found 3 hours ago

Fri, Jun 20 - Thu, Jun 26

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$254 Roundtrip, found 3 hours ago

$254

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Fri, Jun 20 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Thu, Jun 26, priced at $254 found 3 hours ago

Mon, Jun 16 - Tue, Jun 24

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$258 Roundtrip, found 3 hours ago

$258

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Mon, Jun 16 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Tue, Jun 24, priced at $258 found 3 hours ago

Tue, Oct 21 - Wed, Nov 5

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$259 Roundtrip, found 6 days ago

$259

Roundtrip

found 6 days ago

Select JetBlue Airways flight, departing Tue, Oct 21 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Wed, Nov 5, priced at $259 found 6 days ago

Tue, Jul 15 - Wed, Jul 23

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$262 Roundtrip, found 3 days ago

$262

Roundtrip

found 3 days ago

Select Frontier Airlines flight, departing Tue, Jul 15 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Wed, Jul 23, priced at $262 found 3 days ago

Wed, Jun 18 - Wed, Jun 25

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$265 Roundtrip, found 3 hours ago

$265

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Wed, Jun 18 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Wed, Jun 25, priced at $265 found 3 hours ago

Tue, Jun 17 - Tue, Jun 24

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$267 Roundtrip, found 3 hours ago

$267

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Tue, Jun 17 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Tue, Jun 24, priced at $267 found 3 hours ago

Wed, Aug 6 - Sat, Aug 9

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$270 Roundtrip, found 8 hours ago

$270

Roundtrip

found 8 hours ago

Select Frontier Airlines flight, departing Wed, Aug 6 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Sat, Aug 9, priced at $270 found 8 hours ago

Thu, Jun 19 - Wed, Jun 25

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$272 Roundtrip, found 3 hours ago

$272

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Thu, Jun 19 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Wed, Jun 25, priced at $272 found 3 hours ago

Thu, Oct 23 - Wed, Nov 5

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$276 Roundtrip, found 6 days ago

$276

Roundtrip

found 6 days ago

Select JetBlue Airways flight, departing Thu, Oct 23 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Wed, Nov 5, priced at $276 found 6 days ago

Mon, Jun 16 - Wed, Jun 25

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$276 Roundtrip, found 3 hours ago

$276

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Mon, Jun 16 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Wed, Jun 25, priced at $276 found 3 hours ago

Thu, Jun 19 - Thu, Jun 26

DTW

Detroit Metropolitan Wayne County

SJC

Norman Y. Mineta San Jose Intl.

$279 Roundtrip, found 3 hours ago

$279

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Thu, Jun 19 from Detroit Metropolitan Wayne County to Norman Y. Mineta San Jose Intl., returning Thu, Jun 26, priced at $279 found 3 hours ago

Wed, Aug 6 - Thu, Aug 7

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$280 Roundtrip, found 8 hours ago

$280

Roundtrip

found 8 hours ago

Select Frontier Airlines flight, departing Wed, Aug 6 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Thu, Aug 7, priced at $280 found 8 hours ago

Thu, Jul 17 - Mon, Jul 21

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$289 Roundtrip, found 3 days ago

$289

Roundtrip

found 3 days ago

Select Delta flight, departing Thu, Jul 17 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Jul 21, priced at $289 found 3 days ago

Thu, Jul 17 - Mon, Jul 21

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$289 Roundtrip, found 3 days ago

$289

Roundtrip

found 3 days ago

Select United flight, departing Thu, Jul 17 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Jul 21, priced at $289 found 3 days ago

Thu, Jul 17 - Mon, Jul 21

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$309 Roundtrip, found 3 days ago

$309

Roundtrip

found 3 days ago

Select American Airlines flight, departing Thu, Jul 17 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Jul 21, priced at $309 found 3 days ago

Thu, Jul 17 - Mon, Jul 21

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$358 Roundtrip, found 3 days ago

$358

Roundtrip

found 3 days ago

Select Alaska Airlines flight, departing Thu, Jul 17 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Jul 21, priced at $358 found 3 days ago

Thu, Sep 11 - Sat, Sep 27

FNT

Bishop Intl.

SFO

San Francisco Intl.

$389 Roundtrip, found 6 days ago

$389

Roundtrip

found 6 days ago

Select United flight, departing Thu, Sep 11 from Bishop Intl. to San Francisco Intl., returning Sat, Sep 27, priced at $389 found 6 days ago

Mon, Jul 21 - Mon, Jul 21

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$457 Roundtrip, found 3 days ago

$457

Roundtrip

found 3 days ago

Select Hawaiian Airlines flight, departing Mon, Jul 21 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Jul 21, priced at $457 found 3 days ago