Business Hotels in Southern California 2025

Featured Southern California Business Hotels

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
Opens in a new windowThe Sofia Hotel
Sonesta Irvine John Wayne Airport

Sonesta Irvine John Wayne Airport

3.5 out of 5
17941 Von Karman Avenue, Irvine, CA
Fully refundableReserve now, pay when you stay
Opens in a new windowSonesta Irvine John Wayne Airport
Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA

3 out of 5
5975 Lusk Blvd San Diego CA
Opens in a new windowCountry Inn & Suites by Radisson, San Diego North, CA
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Hyatt Regency Irvine

Hyatt Regency Irvine

4 out of 5
17900 Jamboree Rd, Irvine, CA
Fully refundableReserve now, pay when you stay
Opens in a new windowHyatt Regency Irvine
Renaissance Newport Beach Hotel

Renaissance Newport Beach Hotel

4 out of 5
4500 Macarthur Blvd, Newport Beach, CA
Fully refundableReserve now, pay when you stay
Opens in a new windowRenaissance Newport Beach Hotel
Sheraton Gateway Los Angeles Hotel

Sheraton Gateway Los Angeles Hotel

4 out of 5
6101 W Century Blvd Los Angeles CA
Fully refundableReserve now, pay when you stay
Opens in a new windowSheraton Gateway Los Angeles Hotel
Hilton Anaheim

Hilton Anaheim

4 out of 5
777 W Convention Way Anaheim CA
Fully refundableReserve now, pay when you stay
Opens in a new windowHilton Anaheim
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Opens in a new windowWyndham San Diego Bayside
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 out of 5
311 Island Ave San Diego CA
Fully refundableReserve now, pay when you stay
Opens in a new windowThe Horton Grand, Downtown/Gaslamp Quarter
Holiday Inn Carlsbad by IHG

Holiday Inn Carlsbad by IHG

3 out of 5
2725 Palomar Airport Rd, Carlsbad, CA
Fully refundable
Opens in a new windowHoliday Inn Carlsbad by IHG
San Diego Marriott La Jolla

San Diego Marriott La Jolla

4 out of 5
4240 La Jolla Village Dr La Jolla CA
Fully refundableReserve now, pay when you stay
Opens in a new windowSan Diego Marriott La Jolla
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
Opens in a new windowManchester Grand Hyatt San Diego
Ramada Hotel & Conference Center by Wyndham San Diego North

Ramada Hotel & Conference Center by Wyndham San Diego North

2 out of 5
San Diego
Opens in a new windowRamada Hotel & Conference Center by Wyndham San Diego North
HYATT house San Diego/Sorrento Mesa

HYATT house San Diego/Sorrento Mesa

3 out of 5
10044 Pacific Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
Opens in a new windowHYATT house San Diego/Sorrento Mesa
Ontario Airport Hotel & Conference Center

Ontario Airport Hotel & Conference Center

3.5 out of 5
700 N Haven Ave, Ontario, CA
Fully refundableReserve now, pay when you stay
Opens in a new windowOntario Airport Hotel & Conference Center
Urban Boutique Hotel

Urban Boutique Hotel

3 out of 5
1654 Columbia Street San Diego CA
Fully refundableReserve now, pay when you stay
Opens in a new windowUrban Boutique Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
Opens in a new windowBest Western Seven Seas
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4 out of 5
1 Park Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
Opens in a new windowHilton San Diego Bayfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southern California, United States of America
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