Chillicothe Historic Hotels In 2026
Photo by Aaron Littler
Featured Chillicothe Historic Hotels
Christopher Inn and Suites
30 North Plaza Boulevard Chillicothe OH
Fully refundableReserve now, pay when you stay
Holiday Inn Express Chillicothe East by IHG
1003 E Main Street Chillicothe OH
Fully refundable
Best Western Adena Inn
1250 N Bridge Street Chillicothe OH
Fully refundableReserve now, pay when you stay
Save an average of 15% on thousands of hotels when you're signed in
Comfort Inn
7525 US 23 Piketon OH
Hampton Inn & Suites Chillicothe
100 N Plaza Blvd Chillicothe OH
Fully refundableReserve now, pay when you stay
Quality Inn Chillicothe
20 N Plaza Blvd Chillicothe OH
Americas Best Value Inn Chillicothe
1135 East Main Street Chillicothe OH
Ameristay Hotel Inn & Suites Waverly
800 W. Emmitt Ave Waverly OH
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.