Sambú Vacations

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Sambú Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Bella Vista
$947
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
Save 100% on your flight
$1,284
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Beautiful hotel, amazing food, and even better staff. Everyone went above and beyond to genuinely make us feel welcome, and you could tell they took a lot of pride in the hotel and their roles. A special thank you to Jose Luis, Victor, Felix, and the rest of the restaurant staff. They were excellent and a big part of what made our stay so enjoyable. We will definitely be staying at Central Hotel again when we’re back in Panama next year. Highly recommend!

Reviewed on Sep 29, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
$989
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Tocumen Airport
$969
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
I stayed for a layover and it was more than I expected, place was clean and the pool and surrounding area is really nice . Complimentary breakfast was also nice and started early as it caters for the moving travelers . My only issue was the room we took the beds were really small so be mindful of this when booking . Outside of that, this place is a really nice stay .

Reviewed on Sep 30, 2026

Hyatt Regency Panama City

Hyatt Regency Panama City

Bella Vista
$1,053
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Gracias

Reviewed on Sep 29, 2026

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

San Francisco
$1,001
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
St. Louis (STL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
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